Phospholipid polymers hydrogel

Ishiyama N, Moro T, Ishihara K et al (2010) The prevention of peritendinous adhesions by a phospholipid polymer hydrogel formed in situ by spontaneous intermolecular interactions. Biomaterials 31 4009 -016... [Pg.164]

T. Uchiyama, Y. Kiritoshi, J. Watanabe, and K. Ishihara, Degradation of phospholipid polymer hydrogel by hydrogen peroxide aiming at insulin release device. Biomaterials, 24(28), 5183-5190 (2003). [Pg.495]

Ishihara, K., Ueda, T. and Nakabayashi, N. (1990) Preparation of phospholipid polymers and their properties as polymer hydrogel membranes. Polymer Journal, 22, 355-360. [Pg.207]

Cytocompatible Hydrogel Composed of Phospholipid Polymers for Regulation of Cell Functions... [Pg.141]

Keywords Cell encapsulation Cell engineering Cytocompatibility Hydrogel Phospholipid polymers... [Pg.142]

Cytocompatible Polymer Hydrogels Composed of Water-Soluble Phospholipid Polymers... [Pg.147]

Similarly to the phospholipid polymers, the MPC polymers show excellent biocompatibility and blood compatibility [43—48]. These properties are based on the bioinert character of the MPC polymers, i.e., inhibition of specific interaction with biomolecules [49, 50]. Recently, the MPC polymers have been applied to various medical and pharmaceutical applications [44-47, 51-55]. The crosslinked MPC polymers provide good hydrogels and they have been used in the manufacture of soft contact lenses. We have applied the MPC polymer hydrogel as a cell-encapsulation matrix due to its excellent cytocompatibility. At the same time, to prepare a spontaneously forming reversible hydrogel, we focused on the reversible covalent bonding formed between phenylboronic acid and polyol in an aqueous system. [Pg.147]

Kimura M, Fukumoto K, Watanabe J et al (2005) Spontaneously forming hydrogel from water-soluble random- and block-type phospholipid polymers. Biomaterials 26 6853-6862... [Pg.164]

Nam KW, Watanabe J, Ishihara K (2002) Characterization of the spontaneously forming hydrogels composed of water-soluble phospholipid polymers. Biomacromolecules 3 100-105... [Pg.164]

Choi J, Konno T, Matsuno R et al (2008) Surface immobilization of biocompatible phospholipid polymer multilayered hydrogel on titanium alloy. Colloids Surf B Biointerfaces 67 216-223... [Pg.164]

Ishihara K, Ueda T, Nakabayashi N. Preparation of phospholipid polymers and properties as hydrogel membranes. Polym J 1990 22 355-60. [Pg.347]

In our previous studies, we have succeeded in spontaneous gelation of water-soluble phospholipid polymers from their aqueous solutions by hydrogen bonding without any physical treatments (2-7). Also, the hydrogel formed could be dissociated by change in pH, however, the pH inside of the hydrogel was low (pH<4), which would be required in order for its application as a cell container. [Pg.337]

In this study, we synthesized a new water-soluble phospholipid polymer containing a p-vinylphenylboronic acid unit, that is, poly[MPC-co- -BMA-co-/ -vinylphenylboronic acid (VPBA)](PMBV). Also, we reported the synthesis and characterization of the polymer, formation and properties of polymeric hydrogel with PVA, and behavior of fibroblast cells in the hydrogel. [Pg.337]

To demonstrate the application of the hydrogel as a cell-container, mouse fibroblast (L929) cells were cultured (preserved) in the hydrogel. In this culture method, the PMBV631 was dissolved using cell culture medium containing PBS. Previous reports have observed that the phospholipid polymer containing... [Pg.342]

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