Pheromones urinary

Fig. 7.12 Urinary pheromones and Micmcebus populations reproductive influences on Mouse-lemurs. Left weak intra-sexual effects, Right weak inter-sexual effects (c.f. Fig. 7.11) for interactions with photoperiod effects, see text (after Perret, 1992 and 1995 Schilling et al., 1984).

Adams M., Teeter J.H., Katz Y. and Johnsen P.B. (1987). Sex pheromones of the sea lamprey steroid studies on urinary products. J Chem Ecol 13, 387-395. 

Bocskei Z., Groom C., Flower D. Wright C.E., et al. (1992). Pheromone binding to two rodent urinary proteins revealed by X-ray crystallography. Nature 360, 186-188. 

Inamura K. and Kashiwayanagi M. (2000a). Inhibition of fos-immunoreactivity in response to urinary pheromones by beta-adrenergic and serotonergic antagonists in the rat accessory olfactory bulb. Biol Pharm Bull 23, 1108-1110. 

Lawton A.D. and Whitsett J.M. (1979). Inhibition of sexual maturation by a urinary pheromone in male prairie deer mice. Horm Behav 13, 128-138. 

Mucignat-Caretta C., Caretta A. and Baldini J (1998). Protein-bound male urinary pheromones differential responses according to age and gender. Chem Senses 23, 67-70. 

Novotny M., Ma W., Wiesler D. and Zidek L. (1999). Positive identification of the puberty-accelerating pheromone of the house mouse the volatile ligands associating with the major urinary protein. Proc Roy Soc Lond (B) 266, 2017-2022. 

Novotny M., Jemiolo B., Wiesle D., Ma W., et al. (1999). A unique urinary constituent, 6-hydroxy-6-methyl-3-heptanone, is a pheromone that accelerates puberty in female mice. Chem Biol 6, 377-383. 

Robertson D., Benyon R.L. and Evershed R. (1993). Extraction, characterization and binding analysis of two pheromonally active ligands associated with major urinary proteins of house mouse (Mus musculus). J Chem Ecol 19, 1405-1416. 

Sasaki K., Okamoto K., Inamura K., Tokumitsu Y., et al. (1999). Inositol-1,4,5-trisphosphate accumulation induced by urinary pheromones in female rat vomeronasal epithelium. Brain Res 823, 161-168. 

Toftegaard C., Moore C. and Bradley A.J. (1999). Chemical characterisation of urinary pheromones in Brown Antechinus, Antechinus stuartii. J Chem Ecol 25, 527-535. 

Tsujikawa K. and Kashiwayanagi M. (1999). Protease-sensitive urinary pheromones induce region-specific fos-expression in rat accessory olfactory bulb. Biochem Biophys Res Comm 260, 222-224. 

Zidek L., Stone M., Lato S., Pagel M., et al. (1999). NMR-mapping of the recombi mouse major urinary protein-I binding site occupied by the pheromone 2-sec-bi 4,5-dihydrothiazole. Biochem 38, 9850-9861. 

Armstrong, S. D., Robertson, D. H. L., Cheetham, S. A., Hurst, J. L. and Beynon, R. J. (2005) Structural and functional differences in isoforms of mouse major urinary proteins a male-specific protein that preferentially binds a male pheromone. Biochem. J. 391, 343-350. 

Timm, D. E., Baker, L. J., Mueller, H., Zidek, L. and Novotny, M. V. (2001) Structural basis of pheromone binding to mouse major urinary protein (MUP-I). Protein Sci. 10, 997-1004. 

Miyazaki, M., Yamashita, T., Suzuki, Y., Soeta, S., Taira, H. and Suzuki, A. (2006b) A major urinary protein of the domestic cat regulates the production of felinine, a putative pheromone precursor. Chem. Biol. 13, 1071-1079. 

Fig. 17.9 The H assignment of the unlabeled pheromone 2-see-butyl-4,5-dihydrothiazole, bound to [U-13C, 15N]-labeled mouse major urinary protein I, was accomplished by comparing the 2D TOCSY spectrum of free ligand (A) to the 13C-fil-tered TOCSY spectrum of the complex (B). Reproduced with permission from Ref. [37]. Copyright 1999 American Chemical Society.

The female elephant pheromone (Z)-7-dodecenyl acetate occurs bound to urinary proteins. When it is taken up by a male elephant, the acetate is bound to proteins of the trunk mucus. This might facilitate transport of the pheromone to the vicinity of the sensory epithelium of the vomeronasal organ (Rasmussen and Schulte, 1998). 

Rainbow trout Oncorhynchtis mykiss F M Urinary pheromone ll gonadotropin II tr 17,20/SP ll Testosterone ll Milt production Vermeirssen etal., 1997... 

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