Phenylcarboxylic acids

The simultaneous determination of LAS and its potential biodegradation intermediates of low molecular weight (C < 8), as sulfonated and non-sulfonated, has been performed by RP-HPLC-UV using a gradient regime with the mobile phase at pH 2.2 [29]. Compound elution with the same number of carbon atoms in the carboxylic chain was as follows SPCs, hydrophenyl carboxylic acids and finally phenylcarboxylic acids. 

Chiral carboxylates such as a-phenylcarboxylic acids, lactic acid, and mandelic acid were used by Brunner [13], but, as mentioned above, these ligands did not afford very enantioselective catalysts. Aminoacids provided the possibility of introducing bulky substituents at the nitrogen atom, but these ligands based on proline and phenylanaline also gave modest results (Figure 17.12). 

Synonyms AI3-03710 Benzenecarboxylic acid Benzeneformic acid Benzenemethanoic acid Benzoate BRN 0636131 Carboxybenzene Caswell No. 081 CCRIS 1893 Dracylic acid E 210 EINECS 200 618-2 EPA pesticide chemical code 009101 Flowers of benjamin HA 1 NA 9094 NSC 149 Phenylcarboxylic acid Phenylformic acid Retarder BA Retardex Salvo liquid Salvo powder Tennplas UN 9094 Unisept BZA. 

Phenylbutane, see sec-Butylbenzene Phenyl carbinol, see Benzyl alcohol Phenylcarboxylic acid, see Benzoic acid Phenyl chloride, see Chlorobenzene... 

An example of the separation of phenylcarboxylic acids after their conversion into ethyl esters is demonstrated in Fig. 5.10. 

Benzenecarboxylic acid benzeneformic acid carboxybenzene dracylic acid E210 phenylcarboxylic acid phenylformic acid. 

Figure 2 illustrates the Hammett dependences of dissociation equilibria for various substituted phenylcarboxylic acids. 

CAS 65-85-0 EINECS/ELINCS 200-618-2 FEMA2131 INS210 E210 Synonyms Benzenecarboxylic acid Benzene formic acid Carboxybenzene Dracylic acid Phenylcarboxylic acid Phenylformic acid Classification Aromatic acid... 

Phenylcarboxylic acid. See Benzoic acid Phenyl Cellosolve acrylate. See 2-Phenoxyethyl acrylate Phenyl chloride. See Chlorobenzene Phenylchloroform. See Benzotrichloride Phenyl chloromercury. See Phenylmercuric chloride... 

The retention characteristics of over 40 small polar molecules (phenols, phenyl alcohols, imines, phenylcarboxylic acids, phenyl esters, phenyl. ethers, phenyl ketones, nitro- and cyanophenols) were studied on C4 and C g stationary phases [117]. Experimental results explain the advantages of methanol over other organic mobile phase components (e.g., acetonitrile) in the separation of aliphatic alcohols, phenols, and carboxylic acids. Methanol, through its reciprocal hydrogen bond donor/acceptor character forms stable complexes with these solutes in the stationary phase, giving enhanced selectivity for these solute types. The k values for these 40 solutes are tabulated for 20/80, 25/75, and 50/50 methanol/water mobile phases. 

C1-C7 sulfophenylcarboxylic acids, C2-C5 phenylcarboxylic acids, C1-C2 hydroxyphenylcarboxylic acids, C2 di-hydroxyphenylcarboxylic acids separation from each other LAS also determined Bench study SPE of sample (pH 1,30% NaCI, no more than 30 mL) on Cix (elution with acetone or MeOH) RP-HPLC-UV detection (215 nm) 61,64... 

Sulfophenylcarboxylic acids may be synthesized by sulfonation of the corresponding phenylcarboxylic acids (30,64). The C3-3-SPC isomer is useful as an internal standard since it cannot be formed from commercial LAS (33). p-Toluenesulfonic acid has also... 

Fig. 5.10. Gas chromatogram of ethyl esters of phenylcarboxylic adds (2.5 —7.5 Mg). Peaks 1 = benzoic 2 = phenylacetic 3 = 2-phenylpropionic 4 = 2-phenylbutyric 5 = 3-phenylpropionic 6 = 3-phenylbutyric 7 = 4-phenylbutyric 8 = 4-phenylvaleric 9 = 5-phenylvaleric acid S = n-tridecane (internal standard) X = blanks of reagent and products from side-reactions. Conditions column,...

The second type of inhibition, i.e., competitive inhibitors for the amino acid substrates, is that produced by aromatic compounds. Benzoate is a remarkably potent competitive inhibitor of mammalian n-amino acid oxidase (6S, 64)- A detailed study of benzoic acid derivatives as competitive inhibitors has been carried out by Bartlett (64)- The structural unit necessary for inhibition is the phenylcarboxylate ion. Ring substitution has a less marked efiFect, although in general meta substitution, particularly by a halogen, methyl, or nitro group, results in greater inhibitory activity than does substitution in other positions. Benzoate competes with the natural substrates for the holoenzyme and has little or no effect on the apoenzyme. Its inhibitory action is reversible (6S, 65). Heterocyclic acids with aromatic properties (66) are also inhibitors. 

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