2- phenylbenzoic acids

Biphenyl-2-carboxylic (2-phenylbenzoic) acid [947-84-2] M 198.2, m 114 , b 343-344 , pK 3.46. Crystd from C6He-pet ether or aq EtOH. 

Phenylbenzoic Acid. See Biphenylcarboxylic Acid and Derivatives in Vol 2, B125-L... 

R2NC1, 91, 92 phenyl acetate, Fries rearrangement of, 475 phenyacetyl halides, acylation by, 173 2-phenylbenzoic acid, cycliacylation, 185 phenyl ethers, alkylation of, 149 —, bromination of, 130 —, hydrogen exchange with, 260 —, rearrangement of, 476 phenyl ethyl mercury, mercuridemercuration of, 359, 360... 

Tribiphenylcarbinol has been prepared by the action of 4-xenylmagnesium iodide upon 4,4 -diphenylbenzophenone, or upon the methyl ester of -phenylbenzoic acid 1 and by the action of -chlorobiphenyl upon ethyl carbonate in the presence of powdered sodium2 or sodium wire.3... 

Phenylbenzoic acid is converted into benzo[c]coumarin in the Su z system, that is irradiation when mixed with trivalent iodine compounds and iodine the 2-iodo derivative may also be formed <99JCS(P1)1713>. 

Biphenylcarboxylic or Phenylbenzoic Acid(Car-boxydiphenyl), C6H5.CeH4.COOH. Three isomers are known and described in Beil 9,669.671(279, 280) [463,464]... 

Problem 19.18 Write the structure for (a) phenoxyacetic acid, (b) phenyl acetate, (c) 2-hydroxy-3-phenylbenzoic acid, (d) p-phenoxyanisole. M... 

Decomposition of 84 in benzene at 80° yields o-phenylbenzoic acid (50%), polymeric acid (25%), phthalic acid (7%), benzoic acid (5%), carbon dioxide (78%), and a little 3,4-benzocoumarin and diphenyl.72 The first step in this induced decomposition is homolytic cleavage of the peroxide bond.72... 

Hexahydronicotinic acid (90%) is obtained by catalytic hydrogenation of nicotinic acid at 3 atm. pressure over colloidal platinum. Preparation of the catalyst is described. The 9,10 double bond in the acridine nucleus is reduced at 10° by sodium amalgam in dilute sodium carbonate solution to give 9,10-dihydroacridine-S>-carboxylic acid in 70% yield. 2-Phenyl-cyclohexanecarboxylic acid (96%) is prepared by the selective reduction, of 2-phenylbenzoic acid by a large excess of sodium in refluxing amyl alcohol. ... 

More complex cases are very frequent. The choice between 1 -2 -thenoylphenan-threne, 2-l -phenanthroylthiophen, and 1-phenanthryl 2-thienyl ketone for III, or between p-phenylbenzoic acid and diphenyl-carboxylic acid for IV illustrates the principle. The 1945 Chemical Abstracts index lists four methods of naming monoketones. Each... 

Biphenyl-4-carboxylic (4-phenylbenzoic) acid [92-92-2] M 198.2, m 228 , pK 5.66 (in 50 /o 2-butoxyethanol). Crystallise the acid from C6H6/petroleum ether or aqueous EtOH. [Beilstein 9 TV 2479.]... 

A mixture of A,A-diphenylamine (100 mg, 0.592 mmol), 4-phenylbenzoic acid (234 mg, 1.183 mmol), and recrystallized zinc chloride (81 mg, 0.59 mmol) was irradiated in a domestic microwave oven (at 80% of a total output of 1000 W) for 11 min (the reaction was monitored by TLC). The crude product was dissolved in dichloromethane (20 mL) and washed with 10% aqueous NaOH and water. The organic layer was dried (Na2S04), evaporated and the residue crystallized yielding 9-(4-biphenyl)acridine (7, 172 mg, 88% yield). 

HydToxy-2-phenylbenzoic acid, Q-phenylsaii-eylic acid)... 

SCHEME 22.23 Synthesis of phenanthrenes by Pd-catalyzed decarboxylative coupling of 2-phenylbenzoic acids with alkynes. 

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