Phenylbenzoates

The p-phenylbenzoate ester was prepared to protect the hydroxyl group of a prostaglandin intermediate by reaction with the benzoyl chloride (Pyr, 25°, 1 h, 97% yield). It was a more ciystalline, more readily separated derivative than 15 other esters that were investigated. It can be cleaved with K2CO3 in MeOH in the presence of a lactone. ... 

Biphenyl-2-carboxylic (2-phenylbenzoic) acid [947-84-2] M 198.2, m 114 , b 343-344 , pK 3.46. Crystd from C6He-pet ether or aq EtOH. 

Adamantoate, 172 Crotonate, 173 4-Methoxycrotonate, 173 Benzoate, 173 p-Phenylbenzoate, 178 2,4,6 Trimethylbenzoate (Mesitoate), 178... 

Reactions of 19 are similar to those of other A-methylbenzochalcogenium salts. Under the action of NaBH419 is reduced to 3-methyl-2,3-dihydro-2-phenylbenzo-tellurazole. The alkaline hydrolysis of 19 gives rise to di(o-A-methyl-A-benzoyl-aminophenyl) ditelluride (92MI1)... 

Phenylbenzoic Acid. See Biphenylcarboxylic Acid and Derivatives in Vol 2, B125-L... 

R2NC1, 91, 92 phenyl acetate, Fries rearrangement of, 475 phenyacetyl halides, acylation by, 173 2-phenylbenzoic acid, cycliacylation, 185 phenyl ethers, alkylation of, 149 —, bromination of, 130 —, hydrogen exchange with, 260 —, rearrangement of, 476 phenyl ethyl mercury, mercuridemercuration of, 359, 360... 

Methyl 4-methyl-3-[(A -phenylcarbamoyl)imino]-3,4,5,6,7,8-hexahydro-2-quino-xalinecarboxylate (201) underwent cyclization to give lO-methyl-3-phenyl-6,7,8,9-tetrahydrobenzo[g]pteridme-2,4(3//, 10/7)-dione (202) (Et3N, MeOH, reflux, 20 min 80%) and subsequent catalytic aromatization to 10-methyl-3-phenylbenzo[g]pteridine-2,4(3//, 10//)-dione (203) (Pd/C, decahydronaphtha-lene, reflux, 1 h 85%) analogs likewise. ... 

Synthesis of phenylbenzoate from benzoyl Eastman Chemical Leach et al. (1994)... 

Dyrssen, D., Studies on the extraction of metal complexes. XXXII. N-phenylbenzo-hydroxamic acid, Acta Chem. Scand. 10, 353-359 (1957). 

In order to construct the thiepin conjugation, the seven-membered cyclic ketones containing sulfur could be converted to either their enol ethers or enol acetates. The resulting thiepins should have a number of substituents. The first stable 3,5-diacetoxy-4-phenylbenzo[6]thiepin (15) has been obtained by Hofmann et al. from the diketone (14) by acetylation with acetic anhydride in pyridine in good yield 13). By this methodo-... 

Fig. 3. Molecular structure [a] and bond lengths and angles [b] for 3,5-dimethoxy-4-phenylbenzo[ft ]-thiepin 1-oxide (126)...

Systematic studies on benzo[Z>]thiepin 1-oxides were reported by Hofmann and coworkers 82,83). 4-Phenylbenzo[6]thiepin 1-oxides 137a and 137b were prepared via the benzo[h] 3-thiepinone 1-oxide 138 as well as by direct oxidation of the benzo[b]thiepins 139a and 139b, The synthesis of 137c and 137d was only accomplished by the latter way. Further oxidation of 137 yielded the thermally stable 1,1-dioxides. Thermolysis of 137 produced the corresponding naphthalenes by... 

Typical examples are the formation of 3-chloro-2-phenylbenzo[b]-thiophene (21) in near quantitative yield from diphenylacetylene at room temperature,27 and the synthesis of the dichlorothianonane (22) from 1,5-cyclooctadiene.28... 

Tribiphenylcarbinol has been prepared by the action of 4-xenylmagnesium iodide upon 4,4 -diphenylbenzophenone, or upon the methyl ester of -phenylbenzoic acid 1 and by the action of -chlorobiphenyl upon ethyl carbonate in the presence of powdered sodium2 or sodium wire.3... 

Heeramaneck and Shah obtained 3-phenylbenzo[/]quinoline-2-carbox-ylate (908) in good yield on the ring closure of diethyl phenyl(2-naphthyla-mino)methylenemalonate by heating in the melt at 185-195°C (37JCS867). 

Flavonoids are secondary metabolites generally occurring in various plants as glycosides. The chemical structure of flavonoids shows high variety. The basic structure of flavons and flavonols is the 2-phenylbenzo-gamma-pyrone. Flavonoids generally contain two phenol rings linked with a linear three-carbon chain (chalcones) or with three carbon... 

GC analysis of the product on a capillary column shows the diastereomeric purity to be 98.9% (Note 11). Enantiomeric integrity is confirmed after conversion to the corresponding p-phenylbenzoate by HPLC analysis on a chiral column (Note 12). 

C13H10CINO2 t -Chloro-iV-phenylbenzo-hydroxamic acid Photometric V 3... 

C23H29NU8 PBCHA (A-phenylbenzo-18- crown-6-hydroxamic acid) Extraction Ce, La, Th, U 140-142... 

Like cyclobutadiene, azete is very unstable, but it is known in the form of certain derivatives, such as 2-phenylbenzo[/)]azete. This compound can be synthesized in 64% yield by passing a stream of 4-phenyl-1,2,3-benzotria-zoline vapour at low pressure through a tube heated to 420-450 °C. Nitrogen is lost from the starting material, possibly generating a diradical that spontaneously cyclizes to form 2-phenylbenzo[ ]azete (Scheme 8.1). 

When 3-phenylpropynoic acid was combined with perimidine in PPA at 120°C, 6-hydroxy-8-phenylbenzo[g ]per-imidine 939 was obtained <2004RJ0895>. 

The reaction of phenol benzoylation catalyzed by a H-P zeolite (Si/Al ratio 75) has been studied, with the aim of determining the reaction scheme. The only primary product was phenylbenzoate, which then reacted consecutively to yield o- and p-hydroxybenzophenone and benzoylphenylbenzoate isomers, via both intermolecular and intramolecular mechanisms. 

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