Phenyl mercuric nitrate

The mechanism of oxynitration is generally accepted to involve the formation of phenyl mercuric nitrate which reacts with nitrogen oxides in the nitric acid to form a nitroso compound and then a diazonium salt the latter forms a phenol under the aqueous conditions which is then further nitrated. The use of more concentrated nitric acid favours a process of mercuration-nitration and suppresses the formation of phenols. ... 

Chloride Carbon -tetrachloride Chloride reacted with phenyl mercuric nitrate to produce phenyl mercury chloride, then carbon tetrachloride extraction, then GLC 0.4mg L- [799]... 

SYNS FENYLMERKURINITRAT MERPHENYL NITRATE MERSOLITE 7 NITRIC ACID, PHENYL-MERCURY SALT PHE-MER-NITE PHENALCO PHENITOL PHENMERZYL NITRATE PHENYL-MERCURIC NITRATE PHENYLMERCURY NITRATE PHERMERNITE... 

These compounds, e.g., phenyl mercuric nitrate, are very active against Ps. aeruginosa. Concentrations of 10-1000 p.g/ml are inhibitory [55] and they act mainly by inactivating enzymes. 

Studies with preservatives have shown that some combinations are more effective than are the individual constituents alone. Thus, a combination of EDTA and quaternary ammonium compounds is effective [60,63,124]. Also, phenyl mercuric nitrate and phenylethanol, chlorocresol and phenylethanol and EDTA and chlorocresol [124] all show enhanced activity. Polysorbate 80 enhances the activity of polymyxin against Ps. aeruginosa [97] but, unlike EDTA, is unable to enhance the activity of most other agents. 

Phenyl mercuric nitrate 3 0.001% Antivenin (Wyeth-Ayerst) 0.001%... 

Examples of widely used pharmaceutical preservatives include benzoic acid, benzyl alcohol, para hydroxybenzoates, 2 phenylethanol, phenyl mercuric nitrate. Whereas some have been known to suffer from absorption in certain plastics, others have been known to suffer from variable adsorption, which is far less predictable than absorption since it depends on the surface area involved. 

For example, preservatives suffering from adsorption include phenyl mercuric nitrate and acetate benzalkonium chloride thiomersal. Preservatives suffering from absorption include phenol chlorocresol cresol and 2 phenyl ethanol. 

Phenyl mercuric nitrate (PMN) and acetate (PMA) 0.002 Various usages but mercurials queried... 

Phenyl mercuric nitrate, iodoacetate, thiourea, and ammonium sulfate stimulated arsenite-oxidizing activity, whereas cupric ion, and p-chloromercuriben-zoate inhibited it significantly. Legge (8) showed that cytochromes associated with the solid fraction from broken cells of P. arsenoxydans-quinque played a role in aerobic oxidation of arsenite. 

Stabilizer in emulsion, suspending agent, tablet disintegrant, and tablet binder Incompatible with acridine derivatives, crystal violet, phenyl mercuric nitrate and acetate, calcium salts, and alcohol in concentrations greater than 5%, and heavy metals... 

Mercurials. Mercurials, such as mercuric chloride and phenyl mercuric nitrate, exert their antiseptic action on bacteria by combining with essential SH... 

Classification Specially denatured alcohol Definition Ethyl alcohol (100 gal) denatured with (1) potassium iodide USP (80 g) and red mercuric iodide NF (109 g), or (2) thimerosal USP (95 g) or (3) 76 g of any of phenyl mercuric nitrate NF, phenyl mercury chloride NF, or phenyl mercury benzoate... 

Ethylene glycol, 5% aq (cutting fluid) Organosilane solution, 0.1-1% aq (glass coating) Phenyl mercuric nitrate, 0.05% pet (preservative) Polyester resin, 2-5% aq (glass coating) Polysulphide polymer, 1% pet (sealant)... 

Phenylmagnesium chloride Phenylmercuric chloride Phenyl mercuric nitrate 4-(Phenylmethoxy)benzaldehyde... 

Mercurials. Mercurials, such as mercuric chloride and phenyl mercuric nitrate, exert their antiseptic action on bacteria by combining with essential SH groups (Fildes, 1940b). The bacteria appear to be dead, but are easily revived by treatment with a thiol such as thioglycollic acid or even hydrogen sulphide (Chick, 1908). 

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