2-Phenyl ethyl alcohol

In detergent perfumes, the stabiUty of vanillin is not always certain. It depends on the association made with other raw materials, eg, with patchouli, frankincense, cloves, most of the animal notes, and such chemicals as amyl saUcylate, methyl ionones, heflotropin, gamma undecalactone, linalool, methyl anthrarulate, benzyl acetate, phenyl ethyl alcohol, cedar wood derivatives, oak mosses, coumarin, benzoin. Pern balsam, and cistus derivatives. In some cases, these mixtures can cause discoloration effects. 

The soft heavier odours of the cyclo substituted aliphatic alcohols such as benzyl and phenyl-ethyl alcohols. 

Another separation of a mixture of alcohols is often necessary, namely, that of geraniol, citronellol, and phenyl-ethyl-alcohol, all of which occur in admixture in artificial otto of rose. In this case advantage may be taken of the fact that phenyl-ethyl alcohol is easily soluble in 30 per cent, alcohol, which is not the case with geraniol or citronellol. 

Phenyl-ethyl alcohol, CgH. CHj. CHjOH, is the next highest homologue of the benzyl alcohol series. It is found naturally in rose -and neroli oils but as it is very soluble in water, it practically disappears from the distilled otto of rose and is dissolved in the rose water. Hence otto of rose with its beautiful perfume does not truly represent the odour of the rose. By the use of various isolated and synthetic bodies an artificial otto can be prepared which more closely resembles the rose odour than does the natural otto itself. But it is doubtful whether any really good artificial otto of rose can be prepared without some natural otto as its basis. 

Phenyl-ethyl alcohol, or benzyl carbinol, has been known for many years, but its powerful rose odour has been entirely overlooked, its discovery having been made by an ordinary research chemist and not a perfumery expert. Its preparation was described in the Berichte (9, 373) in 1876, but the product there noted was evidently impure, as its boiling-point is recorded as 212°. Commercial specimens vary greatly in both their odour and their keeping properties, some samples deteriorating in odour very rapidly. It is, therefore, very important to -obtain it in a state of the highest purity. It has the following characters —... 

Phenyl-ethyl alcohol can be prepared by numerous methods, several of which are the subject-matter of patents. It may be prepared, for example, by the conversion of phenyl-bromo-lactic acid into phenyl-acetaldehyde, and then reducing this body with sodium. Or it may be prepared by reducing phenyl-acetic esters with sodium and absolute alcohol in the folio-wing manner —... 

It is obtained by allowing a solution of one molecule of phenol-acetic -ester in three to four times its weight of absolute alcohol, to fall in drops on a quantity of sodium calculated for six atoms. It is then heated for several hours on an oil-bath, until the sodium has disappeared, if necessary adding more alcohol. After cooling, water is added, and the ester which is not attacked is saponified. The alcohol and phenyl-ethyl alcohol are then distilled off with steam, when the latter is at once obtained in the pure state. 

It is suitable, not only for rose odours, but also for blending with almost any flower oil. Phenyl-ethyl alcohol forms a solid compound with chloride of calcium, which is very useful for its purification. On oxidation it is converted into a mixture of phenyl-acetaldehyde and phenyl-acetic acid. The last-named body forms an ethyl ester melting at 28°, which serves for its identification. 

Phenyl-propyl alcohol, CgH. CHj. CH.2. CHj. OH, is the next highest homologue of phenyl-ethyl alcohol, and is also known as hydro-cinnamyl alcohol. Like the last described bodies it has been known for many years, its first preparation being described in the Aivnalen (188, 202). It occurs as a cinnamic acid ester in storax, and as an acetic ester in cassia oil. It is prepared synthetically by the reduction of cinnamyl alcohol with sodium amalgam and water, or by the reduction of cinnamic or benzyl acetic esters with sodium and absolute alcohol. It has the following characters —... 

Braun i has shown that alcohols of the type of phenyl-ethyl alcohol, containing an aliphatic and an aromatic radicle, can be prepared by the reduction of nitriles of the general formula X. CN with the corresponding... 

Phenyl-ethyl Acetate.—Phenyl-ethyl alcohol yields a series of highly aromatic esters. That of acetic acid has the formula... 

Phenyl-ethyl Propionate.—The propionic ester of phenyl-ethyl alcohol has the formula CgHj. . OOC. CH CHg. It has a pronounced... 

Early scientific publications detailed experimental results for the enantiosepara-tion of phenyl-ethyl alcohol [30] and on threonine [31]. Sandoz released the first announcement for the development and use of SMB on an industrial scale [32], this separation has been described by Nicoud et al., 1993 [25]. 

In Section 4.3.3 the use of hydrotropes for intensifying multiphase reactions and making them more selective was covered. The key advantage of an aqueous solution of a hydrotrope is that the solute can be recovered by diluting the aqueous solution, after extraction, to a hydrotope concentration below the critical hydrotrope concentration, when a major part of the product will separate out. The diluted solution can then be reconcentrated at reduced pressure to the original concentration for recycle. Thus a number of products of commercial value, such as phenyl ethyl alcohol, can be recovered (Friberg et al 1996 Gaikar and Phatak, 1999). 

Eriobotrya japonica Linkdl. Pi Pa Yie (Loquat) (leaf, flower, fruit) Levulose, sucrose, malic acid, citric acid, tartaric acid, succinic acid, amygdalin, crytoxanthin, carotenes, phenyl ethyl alcohol pentosans, essential oils.50 Antitussive, expectorant, treat bronchitis, cough, fever, nausea, externally applied to epistaxis, smallpox, ulcers. 

Fig. 9. The independence of the heats of exchange on the temperature (a) alcohols on oxide catalyst SB), Reading from left to right allyl, w-propyl, ethyl, i-propyl, i-amyl, n-butyl, phenyl ethyl alcohols, (b) Curve 1—isopropyl alcohol with acetone, curve 2—isopropyl alcohol with hydrogen on MnO (SB).

Basic Formula Phenylethyl alcohol Phenyl ethyl alcohol... 

Geraniol Citronellol beta Damascone Rose oxide Geranium Citronellyl acetate Phenyl ethyl alcohol Orthomethoxy benzyl ethyl ether... 

Phenyl acetaldehyde with phenyl ethyl alcohol or dipropylene glycol (1 1)... 

Figure 9-4 Partition and permeability coefficients relative to LDPE. a) partition in the systems poly-olefin/ethanol and PVC/ethanol b) permeability in polyolefins and PVC. 1 cis-3-hexenol. 2 phenyl-ethyl alcohol, 3 eugenol, 4 isoamyl acetate, 5 undecalactone.

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