Phenol phosphate

Function 3 affects performance as determined by the chemistry of alkylate, carboxyl, sulfonyl, phenolic, phosphate, pyrophosphate, and phosphite groups. 

TMSBr, Pyr, CH2CI2, rt, 1.5 h. Phenolic phosphates were stable to this reagent. 

Two major difficulties must be considered in any assay for acid phosphatase. The enzyme is subject to surface inactivation (23, 24). Accordingly, reproducible initial hydrolytic rates are not always obtained, and the kinetic behavior should be checked in any new assay developed. Discrepancies between the amount of inorganic phosphate produced and phenol liberated from phenolic phosphates may be substantial if extensive phosphotransferase activity occurs because of phosphoryl acceptor action on the part of hydroxylic buffers or other constituents of the incubation mixture (25, 26). Fluorogenic assays have been developed with very high sensitivity (27). Reference will be made to particular assays in the discussion of the specific enzymes. 

In this chapter attention will be focused on the chemical transformations of C02 to yield carboxylic acids and related molecules (e.g., cyclic esters), while natural carboxylations reactions such as those dealing with RuBisCO (ribulose-1,5 bis(phosphate) carboxylase/oxidase) and its genetic engineering or the carboxylation of phenol via a phenol phosphate intermediate by the phenol-carboxylase enzyme, will be left aside. 

Fig. 2.10 Chemical processes which can alter speciation of various elements differ among different soil layers various sediment layers can control passage of heteroelements into deeper soil or sediment strata by chemical reactions, with phenols, phosphate or As(V) retained in corresponding layers whereas other kinds of transformation either directly invoke biological activity (e.g. biomethylation), not to be mimicked by simple element-...

The classical Kolbe-Schmidt reaction treats alkali metal phenoxides and carbon dioxide at higher than atmospheric pressure, giving salicylic acid. Hirao and Kato developed several modifications for industrial production ". Recently, phenol phosphate was enzymatically carboxylated, giving p-hydroxybenzoic acid ". As for related reactions, Sartori and coworkers conducted o-carbamoylation of aluminum or boron phenoxides with alkyl isocyanate ", and Adachi and Sugasawa o-cyanated phenols using methyl thioisocyanate in the presence of BCI3 (equation 54). ... 

Intermediate situations are found for enol and phenol phosphates as weU as for some amides. For these compounds only partial reversibility is observed in vivo. 

Dimethylsulfate, Li0H-H20, THF, reflux, 66-100% yield. K2CO3 in acetone can effectively be used as base and solvent with dimethylsulfate to form esters. A polymer supported methyl sulfate also effectively esterifles carboxylic acids (K2CO3, CH3CN, reflux, 72-99% yield). This reagent also alkylates thiols, phenols, phosphates, and amines. ... 

Various 1,2-dioxetane derivatives have been synthesized and reported. Among them, AMPPD (Adamantyl Methoxy Phenyl Phosphoryl Dioxetane) is a well known dioxetane bearing a spiroadamantyl group at the 3-position and a phenol phosphate at the 4-position, which is now used for chemiluminescence enzyme immunoassay (CLEIA) using alkaline phosphatase with highly sensitive detection. 

After an extensive study, we realized a new 1,2-dioxetane derivative having a fused furan ring and a bulky substituent, t-butyl group, and a phenol phosphate, 5-t-butyl-... 

According to a patent of the Sumitomo Co. (1965), tris-phenol phosphate is prepared from phenol by esterification with phosphorus oxychloride, which is then chlorinated, yielding after hydrolysis a chlorophenol mixture with an ortho para ratio of 8 1. Using sulfuryl chloride (SO2CI2) as chlorinating agent, a chlorophenol mixture of ortho para ratio 4.1 5.7 is formed in the presence of Lewis acid catalysts. 

ACETIC ACID, LEAD(II) SALT TRIHYDRATE (6080-56-4) Pb(C2H302)2 3H20 Contact with acids forms acetic acid. Incompatible with oxidizers, bases, acetic acid alkalis, aUcylene oxides, ammonia, amines, bromates, carbonates, citrates, chlorides, chloral hydrate cresols, epichlorohydrin, hydrozoic acid, isocyanates, methyl isocyanoacetate, phenols, phosphates, salicylic acid sodium salicylate, sodium peroxyborate, potassium bromate resorcinol, salicylic acid, strong oxidizers, sulfates, sulfites, taimin, tartrates, tinctures trinitrobenzoic acid, urea nitrate. On small fires, use dry chemical, Halori, or CO2 extinguishers. 

C4H604Pb Pb(CH3COO)2 Violent reaction with bromates, carbonates, phenols, phosphates potassium bromate (possible explosion). Contact with strong acids forms acetic acid. Reacts with strong oxidizers. Incompatible with alkalis, alkylene oxides, ammonia, amines, carbonates, citrates, cresols, chloral hydrate, chlorides, epichloro-hydrin, hydrozoic acid, isocyanates, methyl isocyanoacetate, phenol, phosphates, potassium bromate, resorcinol, salicylic acid, sodium salicylate, sodium peroxyborate soluble sulfates sulfites, tannin, tartrates, some tinctures triiutrobenzoic acid, urea nitrate. In the heat of fire lead oxides and acetic acid fumes are formed. 

This research was inspired by a remarkable observation by Havinga et al. that in photolysis of the two phenolic phosphates shown in Equation 1.9, the meta isomer hydrolyzed more rapidly than the para counterpart. This not only is the reverse... 

Synonyms Phenolic phosphate Phenylphosphoric acid Phosphoric acid, monophenyl ester Empirical C6H70,P Properties M.w. 174.09... 

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