Personal Genomics

Molecular biologist Leroy Hood anticipates that people will carry credit-card type strips that contain computer readouts of their personal genome. Your entire genome and medical history will be on a credit card .12... 

The key to making such approaches useful is to link the enhanced concentration of a specific sequence with an output that can be measured. More importantly the technology used to detect and report the output signal must be relatively cheap and easy to use if it is to be widely adopted. The cost of a personal genome determination is now relatively low, to the extent individuals underlying medical conditions have been diagnosed based on their symptoms and rapid sequencing. 

Personal Genome Project http // www.personalgenomes.org/ About the personal genome project... 

The Right to Treatment Information. The patient has a right to informed participation in all decisions. .. the risks and serious complications. .. the diagnosis and prognosis. .. the implications of personal genomic and expression array data, ... the existence of any research protocols which are relevant. ... 

Interestingly, the personalized genome services originally envisioned are just now beginning to become a reality. See Anon. Within spitting distance. The Economist, November 22, 2007. 

R 626 P. Workman, The Opportunities and Challenges of Personalized Genome-Based Molecular Therapies for Cancer Targets, Technologies, and Molecular Chaperones , Cancer Chemoth. Pharm., 2003,52(Suppl. 1), S45... 

Maher, B. (2008) Personal genomes the case of missing hereditability. Nature, 456, 18-21. 

While it is probably a number of years in the future, one clinical expectation from the human genome project is that physicians will one day be able to prescribe personal genome readings for patients. The results of such DNA checkups might allow physicians to precisely estimate individual risks for a significant number of common diseases and then provide advice on lifestyle changes, or even prescribe preventive medications. 

Venter, J. C. 2010. Multiple personal genomes await. Nature 464 676-7. 

Brief mention must be made of the tremendous advances that have been made in recent years in the fields of DNA, RNA gene sequencing and synthesis. The development of instrumentation and analysers by the Illumina Company (www.illumina.com/) and the /o torrent semiconductor sequencing of DNA and RNA, using an ion PGM (personal genome machine) sequencer (see http //lifetech-it.hosted.jrvesoftwaie.coni/index.jspa) have made it possible to sequence complete genomes in a matter of weeks or less. 

Sanderson K (2008) Personal genomes standard and pores. Nature 456 23-25... 

Genomics has many applications. Among the most important applications, because of their impact on society, are those that deal with evolution and the environment. Other areas, such as synthetic biology and personal genomics, may lead to innovations that... 

Retail DNA test (Anne Wojcicki) Wojcicki (wife of Google founder Sergey Brin) offers an affordable DNA saliva test, 23andMe, to determine one s genetic markers for ninety traits. The product heralds what Time magazine dubs a personal-genomics revolution. ... 

Ion Torrent Systems Inc. is a major developer of third-generation SMS technology. As its proprietary name, Personal Genome Machine (PGM ), suggests, the main target of Ion Torrent is an individual s genome, which could be sequenced in a very short time at the point of care during a visit to a healthcare... 

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