Pavulon

Pariodel 19 Parcsxetine 54 Patand 53 Pavulon 54 Paxil 54 PCE 32 PCEC54 Pediotic 79 Pendclovir 55 Penetrex 31... 

Pancuronium bromide (Pavulon) is a synthetic bis-quaternary agent containing a steroid nucleus (amino steroid), as denoted by the -curonium suffix. It is five times as potent as d-tubocurarine. Unlike d-tubocu-rarine, it does not release histamine or block ganglionic transmission. Like d-tubocurarine, it has a moderately long onset (2.9 minutes) and duration of action (110 minutes). Pancuronium and its metabolite are eliminated in the urine. 

Pancuronium (Pavulon) [Nondepolarizing neuromuscular Blocker/Para lytic] WARNING Use restricted to experienced personnel Uses Induce paralysis to facilitate ET intubation (RSI) Action Competitive antagonist of acetylcholine Dose Adults Peds. 0.04-0.1 mg/kg IV Maim 0.01 mg/kg q45-60min (onset w/in 1 min duration 30-60 min) Caution [C/-] Cardiac monitor, BP monitor, intubation supplies and ventilator required Contra Use w/ caution in... 

In large doses, injected intravenously, it would bum and hurt horribly, because it s a salt and because it instantly throws off the chemical balance of the blood with which it comes into contact. It makes all muscles lock up in extreme contraction that would hurt unbearably. It wouldn t get to all muscles when a prisoner is being killed with it, however. Since the heart is a muscle and it pumps the blood -- the minute that massive dose of potassium salt hits the heart, one would be history and that would be as far as it would travel. "In lethal injection, three chemicals are used to kill. First, sodium pentothal (its trade name) or thiopental sodium (its chemical name). Then one minute later they inject pavulon. One minute later the potassium chloride. Pentothal is a short acting barbituric acid (barbiturate used in anaesthesia) and is commonly called "truth serum" as it s used in narcoanalysis. It knocks one out. It s a hypnotic. Pavulon is a curare derivative which locks up the lungs so one can t breathe. 

Synonym. Poncuronium Bromide Proprietary Name. Pavulon... 

Op de Coni AA, Lambregts PC, Koeman J, van Puyenbroek MJ, Ter Laak HJ, Gabreels-Festen AA. Neuromuscular complications in patients given Pavulon (pancuronium bromide) during artificial ventilation. CUn Neurol Neurosurg 1985 87(l) 17-22. 

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