Pavulon - Pancuronium bromide

Op de Coni AA, Lambregts PC, Koeman J, van Puyenbroek MJ, Ter Laak HJ, Gabreels-Festen AA. Neuromuscular complications in patients given Pavulon (pancuronium bromide) during artificial ventilation. CUn Neurol Neurosurg 1985 87(l) 17-22. 

Pancuronium bromide (Pavulon) is a synthetic bis-quaternary agent containing a steroid nucleus (amino steroid), as denoted by the -curonium suffix. It is five times as potent as d-tubocurarine. Unlike d-tubocu-rarine, it does not release histamine or block ganglionic transmission. Like d-tubocurarine, it has a moderately long onset (2.9 minutes) and duration of action (110 minutes). Pancuronium and its metabolite are eliminated in the urine. 

Pancuronium bromide (Pavulon) Route IV/IM Pregnancy category C... 

D. Pancuronium bromide (Pavulon, others), 1 and 2 mg/mL in 2-, 5-, and 10-mL vials, ampules (some with benzyl alcohol), and syringes. The suggested minimum stocking level to treat a 70-kg adult for the first 24 hours is eight vials (2 mg/mL, 5 mL each). 

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