Sodium pentothal

Thiourea (H2NCNH2) reacts with diethyl malonate and its alkyl derivatives in the same way that urea does Give the structure of the product obtained when thiourea is used instead of urea in the synthesis of pentobarbital The anesthetic thiopental (Pentothal) sodium is the sodium salt of this product yWhat IS the structure of this compound ... 

Among the barbiturates (see Chapter 30), three compounds, thiopental sodium (Pentothal Sodium), thiamy-lal sodium (Surital), and methohexital sodium Brevital... 

After the September 11, 2001, terrorist attacks in the United States, federal investigators discussed the use of truth serum to obtain information from jailed terrorism suspects. The serum is the barbiturate thiopental, which is also known as pentothal sodium. The use of this drug to make a reluctant person talk has been portrayed in movies, books, and on television. 

As of April 2002, the federal suspects had not been drugged to obtain information. Pentothal sodium cannot force people to be honest. However, an injection of this barbiturate produces a semiconscious state that is like a hypnotic trance. In that state, people s inhibitions are lowered. In that relaxed state, people talk more and could reveal something that they wanted to keep secret. 

Thiopental sodium (Pentothal sodium) IV infusion reconstiuted Sodium carbonate pH 10-11... 

Thiopental Sodium, USP. Thiopental. sodium, sodium S-ethyl-S-(l-methylbutyl)-2-lhiobarbilurale (Pentothal Sodium). is the mo.st widely u.sed ultra-short-acting anc.sthctic barbiturate. Additionally, the compound is the prototype for the ultra-short-acting barbiturates. Most discussions of how structure influences duration of action in this group of agents relate specifically to it. The compound s onset of action is about equal to the time required for it to travel to the brain from the site of administration. Consciousness is regained within 30 minutes. 

Pentothal Pentothal Sodium Intraval Sodium ) is a barbiturate used for intravenous induction of anaesthesia, or as an intravenous general ANAESTHETIC for short operations. It is also used as an ANTICONVULSANT in short-term control of convulsive states. 

Thiopental Sodium, 5.Ethyldihydro-5 ( I-methyl-butyl)-2-thioxo-4,6(lH,SH)-pyrimidinedione monosodium salt 5-ethyl-5-iI-methy(butyl)-2-thiobarbituric acid sodium salt thiomebumal sodium penthiobarbital sodium thiopen -tone sodium thionembutal Pentothal Sodium Nesdonal Sodium Intraval Sodium Trapanal Thiothal Sodium. C,.-Hl7N2Na02S mol wt 264.33. C 49.98%, H 6,48%, N 10.60%, Na 8,70%, O 12-11%, S 12.13%. Prepn U.S. pats. 2,153,729 (1939) 2,876,225 (1959). Prepn of nonhygrosopic crystals Hartop, U.S. pat. 3,109,001 (1963 to Abbott). Acute toxicity Christensen, Lee, Toxicol. Appl. Pharmacol. 26, 495 (1973). 

Pentothal sodium (Abbott) Intraval sodium (May and Baker)... 

Pentothal Sodium, Nesdonal Sodium, Intraval Sodium, Trapanal, Thiothal Sodium, Faimotal, Hypnostan, Sandotfaal [1,3]. 

---