Parophrys vetulus

Malins DC, MM Krahn, MS Myers, LD Rhodes, DW Brown, CA Krone, BB McCain, S-L Chan (1985) Toxic chemicals in sediments and biota from a creosote-polluted harbor relationships with hepatic neoplasms and other hepatic lesions in English sole (Parophrys vetulus). Carcinogenesis 6 1463-1469. 

Collier, T.K. and U. Varanasi. 1991. Hepatic activities of xenobiotic metabolizing enzymes and biliary levels of xenobiotics in English sole (Parophrys vetulus) exposed to environmental contaminants. Arch. Environ. Contam. Toxicol. 20 462-473. 

Following an aviation kerosin spill, hydrocarbons were detected in trout stream sediments and fish up to 14 months after the spill [13]. After a fire at a weed treatment plant in 1970 a large area of mixed forested ecosystem became contaminated with polycyclic aromatic hydrocarbons and creosote [66], High polyaromatic concentrations in stream sediments adversely affected micro- and meiobenthic communities at all trophic levels. Stein et al. [67] have studied the uptake by bethnic fish (English sole, Parophrys vetulus) of benzopyrene and polychlorinated biphenyls from sediments. Accumulation of contaminants from sediments was a significant route of uptake by English sole. 

Malins, D.C., Krahn, M.M., Brown, D.W., Rhodes, L.D., Myers, M.S., McCain, B.B., Chan, S.L. (1995). Toxic chemicals in marine sediment and biota from Muldlteo, Washington Relationships with hepatic neoplasms and other hepatic lesions in EngUsh sole Parophrys vetulus). JNatl Cancer Inst 74 487 94. 

Krahn, M.M., L.D. Rhodes, M.S. Myers L.K. Moore, W.D. MacLeod, Jr., and D.C. Malins. 1986. Associations between metabolites of aromatic compounds in bile and the occurrence of hepatic lesions in English sole Parophrys vetulus) from Puget Sound, Washington. Arch. Environ. Contam. Toxicol. 15 61-67... 

Vanarasi, U., Reichert, W.L. and Stein, J.E. (1989) 32P-post-labelling analysis of DNA adducts in liver and wild English sole (Parophrys vetulus) and winter flounder (Pseudopleuronectus... 

Experimental and environmental oncology in fish has been under study for more than 40 years, and a number of favorites have made it to the forefront rainbow trout (Oncorhynchus mykiss), Xiphophorus spp. and medaka (Oryzias latipes) in the realm of tank-held experimental models. Likewise, there are naturally occurring epizootics of cancer that have proven to be worthy models of study including the English sole (Parophrys vetulus), mummichog (Fundulus heteroclitus) and shad (Dorosoma... 

Brown, D.A. Increases of Cd and the Cd Zn ratio in the high molecular-weight protein pool from apparently normal liver of tumor-bearing flounders (Parophrys vetulus). Mar. Biol. 44 203-209, 1977. 

Utter, F.M. and G.J. Ridgeway. A serologically detected serum factor associated with maturity in the English sole, Parophrys vetulus and Pacific halibut, Hippoglossus stenolepis. US Fish Wildl. Serv. Fish. Bull. 66 47-48, 1967. 

Dihydro dihydroxynaphthalene English sole, Parophrys vetulus liver. Bile 20... 

English sole, Pleuronectes vetulus/Parophrys vetulus, 47... 

Malins DC, Myers MS, Roubal WT (1983) Organic free radicals associated with idiopathic liver lesions of English sole Parophrys vetulus) from polluted marine environments. Environ Sci Technol 17 679-685... 

A few studies have examined tissue-sediment correlations of PAHs in fish, usually with indicators of exposure other than concentrations of parent compounds in tissue. Studies with English sole Parophrys vetulus) have shown a dose-response relationship between exposure to benzo [a] pyrene or PAH-rich sediment extract and benzo [a] pyrene-like bile fluorescence levels (Collier and Varanasi 1991). Moreover, a wide range of fish species from sites with increased sediment concentrations of PAHs have demonstrated... 

Collier TK, Stein JE, Wallace RJ, Varanasi U (1986) Xenobiotic metabolizing enzymes in spawning English sole (Parophrys vetulus) exposed to organic-solvent extracts of marine sediments from contaminated and reference areas. Comp Biochem Physiol 84C 291-298. 

Johnson LL, Casillas E, Collier TK, McCain BB, Varanasi U (1988) Contaminant effects on ovarian development in English sole (Parophrys vetulus) from Puget Sound, Washington. Can J Fish Aquat Sci 45 2133-2146. 

Landahl JT, McCain BB, Myers MS, Rhodes LD, Brown DW (1990) Consistent associations between hepatic lesions in English sole Parophrys vetulus) and polycyclic aromatic hydrocarbons in bottom sediment. Environ Health Perspect 89 195-203. 

Reichert WL, Varanasi U (1982) Metabolism of orally administered naphthalene in spawning English sole Parophrys vetulus). Environ Res 27 316-324. 

Varanasi U, Nishimoto M, Reichert WL, Stein JE (1982) Metabolism and subsequent covalent binding of benzo[a]pyrene to macromolecules in gonads and liver of ripe English sole Parophrys vetulus). Xenobiotica 12 417-425. 

Casillas, E. Misitano, D. Johnson, L.L. Rhodes, L.D. Collier, T.K. Stein, J.E. Mccain, B.B. Varanasi, U. 1991. Inducibility of spawning and reproductive success of female English sole (Parophrys vetulus) from urban and nonurban areas of Puget Sound. Marine Environmental Research, v.31, p.99-122. 

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