Pancreozymin

Cholecystokinin, CCK or pancreozymin (gallbladder, pancreas), many forms exist CCK 58 58 ... 

Cholecystokinin (= Pancreozymin)] (4kDa protein) Animals brain GI tract CCK-R agonist ianorexigenic, nociception, T pancreatic exocrine secretion, J- gastric emptying]... 

It was thought originally that choiccystokinin and pancreozymin were two different hormones. Cholecyslokinin wa<... 

II. Comparative response following test meal or injection of secretin and pancreozymin. Am. J. Dig. Dis. 11, 685-694. 

Somatostatin has been found to inhibit the secretion of various other hormones such as thyrotropin, gastrin inhibitory peptide (GIP), vasoactive intestinal peptide (VIP), pancreozymin, secretin, motilin, gastrin, renin, ACTH in patients with ACTH-secreting pituitary adenoma and ACTH-secretion vitro and to effect exocrine pancreatic function and various GI functions. "21 The physiological significance of these findings is not clear at the present time. 

Protein, blood Secretin-pancreozymin Sweat electrolytes test... 

Lumbar puncture and cerebrospinal fluid examination Paracentesis Pericardiocentesis Secretin-pancreozymin Semen analysis Sims-Huhner test Sweat electrolytes test Tau protein... 

Raper, J. Physiol. (London) 102, 115 (1943). Identity with pancreozymin Jorpes et at., Acta Chem Scand. 18, 2408 (1964). The C-terminal pentapeptide has been shown to be identical to that of gastrin and caerulein V, Mutt, J. E. 

C-terminal octapeptide SQ 19844 Kinevac. C H N -OjjS mol wt [143.29. C 51.48%, H 5.47%, N 12.25%, O 22.39%, S 8.41%. The C-terminal octapeptide of choleeys-tokinin-pancreozymin (see cholecystokinin). Structurally similar to caerulein, q.v., it evokes a variety of biological responses similar to CCK-PZ, includiug smooth-muscle contraction of the gall bladder and small intestine, relaxation of the choledochoduodenal junction, protein secretion by the pancreas and acid secretion by the stomach. It is more active than cholecystokinin on a weight or molar basis. Initial isoln V. Mutt, J. E. Jorpes, Eur. J. Biochem. 6, 156 (1968). Prepn M. A. Ondetti et al. Get. pat. 1,922,185 corresp to U.S. pat, 3,723,406 (1969, 1970, both to Squibb) eidem, J. Am. Chem. Soc. 92, 195 (1970), Mechanical and metabolic effects K. E. Andersson ef al., Acta Physiol... 

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