Palladium II Chloride

Nishiguchi, T. Tanaka, M. Rukuzumi, K., Chem Lett. 1976, 855. 

Stuart J. Mahoney Eric Pillion University of Waterloo, Waterloo, Ontario, Canada 

Solubility slightly sol H2O sol H2O in the presence of chloride ion sol aqueous HCl sol PhCN, forming Pd(PhCN)2Cl2 insol organic solvents. 

Form StqtpUed in commercially available as a mst-colored stable powder or crystalline soM. 

General Considerations. Many of the reactions described below can be accomplished using derivatives of palladium chloride such as potassium tetrachloropaUadate(II), disodium tetra-chloropalladate(II), Bis(benzonitrile)dichloropalladium(II), dichlorobis(acetonitrile)palladium, and dichloro- 

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In a lOOmL round-bottomed flask fitted with a magnetic stirrer is placed a mixture of palladium (II) chloride (89mg, O.Smmol), p-benzoquinone (5.94g, 55mmol) and 7 1 dimethylformamide/water (20mL). To the solution, t-decene [substitute safrole for this compound) (7.0g, 50mmc4) is added in 10 min and the mixture is stirred at room temperature for 7h. The solution is poured into cold 3 normal hydrochloric acid (lOOmL) and extracted with 5 portions of ether. The extracts are combined and washed with three portions of 10% aqueous sodium hydroxide solution and a portion of brine, and then dried After removal of the solvent, the residue is distilled to give 2-decanone [P2P] yield 6.1g (78%). 

Example 68 Add. 1 mole of 3-(3,4-methylenedioxyphenyl) propylene,. 25 mole of methyl nitrite,, 5L of methanol, 36g of water,. 006 mole of bisfbenzonitrile) palladium (II) chloride as a catalyst to a flask. Stir magnetically for 1.5 hours at 25C. The conversion of the starting material was 100%, the yield of MDP-2-P was 88%. 

Palladium (II) chloride [7647-10-1 ] M 177.3, m 678-680". The anhydrous salt is insoluble in H2O and dissolves in HCl with difficulty. The dihydrate forms red hygroscopic crystals that are readily reduced to Pd. Dissolve in cone HCl through which dry CI2 was bubbled. Filter this solution which contains H2PdCl4 and H2PdCl6 and on evaporation yields a residue of pure PdQ2. [Handbook of Preparative Inorganic Chemistry (EdBrauer) Vol 2 1582 7965 Org Synth Coll Vol III 685 1955.]... 

Bis(benzonitrile)palladium(II) chloride, benzene, reflux, 16-20 h, 86% yield. 

Hydrogen is a colourless, tasteless, odourless gas which has only low solubility in liquid solvents. It is comparatively unreactive at room temperature though it combines with fluorine even in the dark and readily reduces aqueous solutions of palladium(II) chloride ... 

Pallado-. palladous, palladium (II). -chlorid, n. palladous chloride, palladium(II) chloride, -chlorwasserstoffsaure, /. chloropalladous acid, chloropalladic(II) acid, -hydro d, n. palladous hydroxide, palladium(II) hydroxide. 

In the presence of triphenylphosphine and four equivalents of chloride, (1-butyl-3-methylimida2olylidene)bis(triphenylphosphine)palladium(II) chloride is formed (Scheme 6.1-4). 

The Wacker process uses an aqueous solution of palladium(II) chloride, copper(II) chloride catalyst system. 

Palladiumphthalocyanine (PcPd) can be synthesized from phthalimide, ammonium molyb-date(VI), urea and palladium(II) chloride in nitrobenzene.285 Peripherally substituted palladium phthalocyanine is prepared by the reaction of phthalonitrile286 or isoindolinediimine114,117 and palladium(II) acetate in 2-(dimethylamino)ethanol. Also a metal insertion into metal-free phthalocyanine in dimethylfonnamide starting from bis(triphenylphos-phane)palladium(II) chloride has been performed.141,287... 

Cooper(I) carboxylates give esters with primary (including neopentyl without rearrangement), secondary, and tertiary alkyl, allylic, and vinylic halides. A simple Sn mechanism is obviously precluded in this case. Vinylic halides can be converted to vinylic acetates by treatment with sodium acetate if palladium(II) chloride is present. ... 

Dipping solution Dissolve 500 mg palladium(II) chloride in 2.5 ml hydrochloric acid (321 0) and make up to 100 ml with ethanol [10]. 

Palladium(II) chloride forms colored complexes with many aromatic and sulfur-containing compounds [27]. 

Palladium catalyst, 59,160 Palladium(II) chloride, 59,161 Paraformaldehyde, 56,40 Pentachlorophenyllithium, 59, 72 frans-2,4-Pentadienoic acid, 59, 1 2,4-Pentadienoic acids, 59, 6... 

Very recently, well-defined complexes with general formula [PdCl(T -Cp) (NHC)] were synthesised and tested for the homocoupling of non-electrodeficient arylboronic acids at room temperature with good results (Scheme 7.7) [51]- This new class of catalysts were synthesised from commercially available NHC palladium(II) chloride dimers and are air-stable. 

In the ligand l,2-bis-(2-pyridylethynyl)benzene the pyridyl N atoms easily attain the appropriate separation for trans-chelation of metal cations. The 1 1 complex of the ligand with palladium(II) chloride has been structurally characterized.171,182... 

Palladium (II) chloride and ferric (III) chloride were purchased from Sigma Chemicals Co. Cerium(III) nitrate from Pfaltz Bauer, Inc. y-Al203 (100 m2/g) from Alfa Chemicals ethanol (HPLC grade) and nitrobenzene (Certified ACS) from Fisher Scientific. Bis(triphenylphosphine)palladium(II) dichloride was generously donated by Dr. Ivan J.B. Lin (National Dong Hwa University, Taiwan). All compounds were used without further treatment. Carbon monoxide (99.0%) was obtained from Praxair. 

Only one report mentions the cyclopropanation with diazodiphenylmethane in the presence of a group VIII metal catalyst. Remarkably enough, the selectivity of the reaction with 5-methylene-bicyclo[2.2.1]hept-2-ene (8) can be reversed completely. With Rh2(OAc)4 as catalyst, the exocyclie double bond is cyclopropanated exclusively (>100 1), whereas in the presence of bis(benzonitrile) palladium(II) chloride the endocyclic C=C bond is attacked with very high selectivity (>50 1)47). 

CIO ] was prepared in this manner from palladium(II) chloride (475), and similarly [Pd(dien)(S-Me2S0)][C104]2 (116) and... 

The palladium nanoparticle is prepared from the reaction of the stabilizer, 4,4 -bis(perfluorooctyl)dibenzylideneacetone with palladium(II) chloride. The average size of the nanoparticle varied according the ratio of PdCF to the stabilizer, but was typically around 4 or 5 nm. The initial yield observed in the Suzuki coupling reaction was 90%, but decreased to 78% after five consecutive runs. Fluorous boronates (alternative precursors in Suzuki reactions), have also been developed for use in fluorous biphasic processes [12], A generic structure of a fluorous boronate is shown in Figure 10.2. 

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