Painful bladder syndromes

A device with shape memory technology and osmotic delivery has been developed to treat patients who suffer from a painful bladder condition known as interstitial cystitis/bladder pain syndrome (TARIS Biomedical Inc., MA). The device was made of a dual-lumen silicone catheter with one lumen loaded with lidocaine, which continuously leached out as contacted with urine. The second lumen of the device contains superelastic nitinol wire in a predefined form, which provides the... 

Unlabeled Uses Bladder instability complex regional pain syndrome (CRPS), pros-tatic obstruction, Raynaud s disease... 

Xi Xin is a very pungent and hot herb with an aromatic smell. It does not enter the Bladder meridian, but does enter the Kidney meridian. It can be selected as deputy in the formula to enhance the action of the chief herbs in treating an excess condition of wind-cold syndrome and can release pain. 

Gui Zhi is sweet and warm, and primarily enters the Heart meridian. It has an aromatic smell that gives this herb a thin pungent property, which makes it move quickly and lightly. It can particularly warm the blood, stimulate the Heart and promote the blood circulation thus it can treat cold hands and feet, cramp of the muscles and pain due to cold obstruction of the blood circulation. In addition, Gui Zhi also enters the Lung and Bladder meridians, is able to expel wind and cold in the superficial region and can therefore treat exterior wind-cold syndrome. 

This formula can clear heat, drain excess fire, promote urination and relieve pain. It is used to treat Lin syndrome (painful urinary dysfunction) due to damp-heat in the Bladder, which injures the blood and blocks the Qi. The manifestations are turbid and dark urine, painful and difficult urination, lower abdominal pain and distension, dry mouth and thirst, a yellow and sticky tongue coating, and a slippery and wiry pulse. 

A 15-year-old boy with Lennox-Gastaut syndrome taking felbamate (3000 mg/day), topiramate(200 mg/ day), and lorazepam developed painful hematuria, bilateral urethral obstruction, and urinary retention. Kidney, bladder, and urethral stones were found. The stone material was identified as felbamate by chemical analysis. However, as the patient was also taking topir-amate the association with felbamate was uncertain. 

Congestive heart failure Hypertension Deep vein thrombosis Coronary artery disease Stroke Diabetes Insulin resistance Glucocorticoid imbalance Gall bladder disease Hypercholesterolemia Hypertriglyceridemia Gout Pancreatitis Liver disease Osteoarthritis Rheumatoid arthritis Bone fractures Lower back pain Carpal tunnel syndrome Depression Pain... 

Nickel, J. C., et al. (2012). Continuous intravesical lidocaine treatment for interstitial cystitis/ bladder pain syndrome safety and efficacy of a new drug dehvery device. Science Translational Medicine, 4(143), 143ral00. 

Acute intoxication produces a predominantly stimulant picture (Appendix A6). Whilst there s no clear withdrawal syndrome, patients may be anxious, agitated, and conplain of pain (especially bladder-related). Unless acutely psychotic and in need of a psychiatric admission, these patients are best treated by addiction services. 

Fig. 4. 33. Bouveret syndrome A large gall bladder stone has eroded into the second part of the duodenum, causing pain, fever, and symptoms of gastric outlet obstruction...

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