Oxidant stress in brain

Oberdorster E (2004) Manufactured nanomaterials (fullerenes, C60) induce oxidative stress in brain of juvenile largemouth bass. Environ Health Perspect. 112 1058-1062. 

It has been proposed that FRs influence the aging process and that they are implicated in neurodegeneration, which is present in senile AD. Increased levels of FRs in frontal areas and an increase of the oxidative stress in brains of patients with AD have been found (C. D. Smith et al. 1991). Although the role of FRs in the pathogenesis of AD remains unclear, the antioxidant or specific therapies directed to neutralize the toxic effects of these products may be beneficial, especially if the microglia is, as it seems, a great FR source. 

Love S. (1999). Oxidative stress in brain ischemia. Brain Pathol. 9 119-131. 

Floyd R. A. and Hensley K. (2002). Oxidative stress in brain aging-implications for therapeutics of neurodegenerative diseases. Neurobiol. Aging 23 795-807. 

F9. Fontella, F. U., Pulrolnik, V., Gassen, E., Wannmacher, C. M., Klein, A. B., Wajner, M., and Dutra-Filho, C. S., Propionic and L-methylmalonic acids induce oxidative stress in brain of young rats. Neuroreport 11, 541-544 (2000). 

Juurlink, B.H., and Paterson, P.G. 1998. Review of oxidative stress in brain and spinal cord injury suggestions for pharmacological and nutritional management strategies. J Spinal Cord Med 21 309-334. 

Mariani E., Polidori M.C., Cherubini A. et al. Oxidative stress in brain aging, neurodegenerative and vascular diseases an overview. J. Chromatogr. B. Analyt. Technol Biomed. Life Sci. 2005, 827 65-75. 

Decreased accumulation of protein carbonyls (markers of oxidative stress) in brain C57Bty6 mice... 

H., Mikawa, S., Kondo, T., et al.. Transgenic mice and knockout mutants in the study of oxidative stress in brain injury, J. Neurotrauma, 12(5), 815, 1995. 

Lam HR, Ostergaard G, Guo SX, et al. 1994. Three weeks exposure of rats to dearomatized white spirit modifies indices of oxidative stress in brain, kidneyO and liver. Biochem Pharmacol 47(4) 651-657. 

Love S (1999) Oxidative stress in brain ischemia. Brain Pathol 9 119-131 Lu A, Tang Y, Ran R, Clark JF, Aronow BJ, Sharp FR (2003) Genomics of the periinfarction cortex after focal cerebral ischemia. J Cereb Blood Flow Metab 23 786-810 Luo Y, Ji X, Ling F, Li W, Zhang F, Cao G, Chen J (2007) Impaired DNA repair via the base-exdsion repair pathway after focal ischemic brain injury a protein phosphorylation-dependent mechanism reversed by hypothermic neuroprotection. Front Biosci 12 1852-1862 Ma Y, Hendershot LM (2004) ER chaperone functions during normal and stress conditions. J Chem Neuroanat 28 51-65... 

Schuck PF, et al. Acute renal failure potentiates meth-ylmalonate-induced oxidative stress in brain and kidney of rats. Free Radic Res. 2013 47(3) 233-40. 

Joshi, G., S. Hardas, R. Sultana et al. Glutathione elevation by ganuna-glutamyl cysteine ethyl ester as a potential therapeutic strategy for preventing oxidative stress in brain mediated by in vivo administration of adriamycin Implication for chemobrain. 

Tyagi N, Moshal KS, Sen U, Vacek TP, Kumar M, Hughes WM Jr., Kundu S, Tyagi SC, 2009. H2S protects against methionine-induced oxidative stress in brain endothelial cells. Antioxid Redox Signal n l) 25. 

Price TO, Ercal N, Nakaoke R et al (2005) HIV-1 vital proteins gpl20 and Tat induce oxidative stress in brain endothelial cells. Brain Res 1045 57-63... 

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