Other Platinum-Containing Anticancer Compounds

Coordination compounds have become very usable in medicine [361-364]. In this respect, use of metal complexes (mostly those of lanthanides) as diagnostic [365-367] and anticancer [368-370] media should be specially emphasized. Among the last complexes, the aminoplatinum-containing compounds play an important role, so the structural study of platinum complexes as a model of nucleobases [371] is a topic of renewed interest. The new issue of Comprehensive Coordination Chemistry II [372] contains a wide description of nanoparticles (vols. 6 and 7), biocoordination chemistry (vol. 8), and other aspects of application of coordination compounds. 

The use of organotin-containing compounds as potential drugs in the war against cancer has occurred since the early 1970s with some but only mild suc-cess. We more recently began to focus on the anti-cancer activity of organotin polymers that we had made for other purposes and as part of our platinum anticancer effort. Here, we will briefly review these efforts. 

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