Osteoporosis predisposing factors

Predisposing factors for low back pain include osteoporosis, trauma and pregnancy. 

Advanced age is a common predisposing factor to the development of osteoporosis. 

Identify risk factors that predispose patients to osteoporosis. 

It can occur in the presence of particular hormonal disorders and chronic diseases, or as a result of medications, specifically glucocorticoids (steroid- or glucocorticoid-induced osteoporosis). A major risk factor for osteoporosis in both men and women is advanced age. In females, oestrogen deficiency following menopause is correlated with a rapid reduction in BMD, while in men a decrease in testosterone has a comparable (bnt less pronounced) effect. European or Asian ancestry predisposes for osteoporosis. 

Osteoporosis is a prevalent disease that typically reduces bone strength and predisposes to fractures. It is a multifactorial disorder resulting from the interaction of genetic and acquired factors. Candidate gene studies and, more recently, genome-wide studies have identified a number of polymorphisms significantly associated with bone mass and fractures. Anti-resorptive drugs, which inhibit the differentiation and activity of osteoclasts, are frequently used to treat patients with osteoporosis. 

Osteoporosis is a disablirtg disorder that is characterized by decreased borte strertgth, which predisposes patients to an increased risk of bone fracture. Peak bone mass (maximum bone strength and density) is normally attained by age 20-25. Age, race, sex, environment, and lifestyle factors such as physical activity and diet are important determinants of bone density. With the increase in age, the rate at which bone tissue is replaced is reduced in comparison to the rate at which it is lost, which increases the risk for fractures. 

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