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Orphan receptors characterization

There are also orphan receptors known which bind as monomers to asynnnetric recognition sequences (fig. 4.7d). The function of these receptors is still poorly characterized. [Pg.157]

The ligand binding pocket of USP is filled by a fortuitous phospholipid co-purified and co-crystallized with the USP LBD that was fiirther characterized by mass-spectroscopic and chemical analysis [57]. In a similar way, recent crystallographic investigations of the retinoid-acid related orphan receptor (3 (ROR (3) [58] and of the heterodimeric complex RARa/RXRa [30] revealed an E.coli endogeneous fatty acid in the ROR (3 and in the RXRa subunit, respectively. [Pg.186]

Maenhaut, C. Van Sande, J. Massart, C. et al. The orphan receptor CDNA RDC4 encodes a 5-HTlD serotonin receptor. Biochem. Biophys. Res. Commun. 1991,180, 1460-1468. Ames, R.S. Li, T. Sarau, H.M. et al. Molecular cloning and characterization of the human anaphylatoxin C3a receptor. J. Biol. Chem. 1996, 271, 20231-20234. [Pg.3127]

Lee CH, Chinpaisal C, Wei LN. 1998. Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2.Mo/. Cell. Biol. 18 6745-55... [Pg.71]

The molecular knowledge of GPCRs as information processing units continues to progress at an impressive pace [4, 120], Besides the many efforts and opportunities on orphan receptors, GPCR research focuses on deeper characterization of GIP networks and receptosomes. [Pg.968]

Law, N.M. and Rosenzweig, S.A. (1994) Characterization of the G-protein linked orphan receptor GPRNl/RDCl. Biochemical and Biophysical Research Communications, 201, 458-465. [Pg.174]


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See also in sourсe #XX -- [ Pg.3108 ]




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