Organotin complexes

Saxena, A., J.K. Koacher, and J.P. Tandon. 1985. Testicular changes in rats after administration of organotin complex. Jour. Toxicol. Environ. Health 15 503-507. 

Dibutyltin glycylglycinate 44 (where R = butyl) is the most active organotin complex against p388 leukemia, but is inactive against L1210 leukemia, B16 melanoma, and Lewis lung carcinoma in mice (212). 

Naked tin adatoms have also been obtained on a Pt/Si02 catalyst but, to remove all the butyl ligands the grafted organotin complex was further heated at 300 °C. In agreement with the gas evolution of four butane equivalents per tin. 

A very large series of organotin complexes of the types SnKj(RCOCHCOCH2COR ) and (SnK RCOCHCOCHCOR ) (R, R, R" = alkyl, phenyl) has been prepared. Both E and Z enoi... 

Organotin complex 59 has been used in the kinetic resolution of 1,2-diols [55]. This catalyst is postulated to react with the diol to form a stannylene acetal that is subsequently benzoylated. Utilization of Na2C03 as a solid base and addition of controlled amounts of water allow for resolution of certain diols with modest to good selectivities (/crc[=3.2-22.4, when enantiomeric excesses are corrected for the ee of catalyst, see Scheme 14) [56]. 

The 119Sn chemical shifts of some discrete five- and six-coordinate organotin complexes are collected in Table X. 

Sn chemical shifts (ppm) of some discrete organotin complexes... 

A high-yield general route to organotin complexes of osmium has been found... 

Treatment of [OsH2(CO)4] with tin oxides, alkoxides, or amines has yielded organotin complexes of the type trun.s-[Os(SnR3)2(CO)4] (R3 = Ph3, Bu3, or... 

As for monoanions, the crystal structures of the only diorganotin derivative 473930, two mono-organotin complexes 474a and 474b931, and a number of anions of the type 475 have been described. Selected structural parameters for these compounds are given in Table 66. 

Organotin complexes of di(2-pyridyl) ketone 2-thenoylhydrazone, 1 and 2, with 6- and 5-coordinated tin atom are less active than the parent organotins67,68. Compound 2 showed good results in tests against Bacillus subtilis, Staphylococcus aureus and also toward several Bacilli with minimum inhibitory concentration ranging from 1.5 to 3 pgml-167. At the same time this complex is devoid of DNA-damaging activity in the Bacillus subtilis rec-... 

The selected organic salts of Ba, Cd, Zn, Sn, Pb, and Ca perform with varying degrees of acceptability. Barium-cadmium and barium-cadmium-zinc are the most widely used tin mercaptides and organotin complexes are utilized where ultimate clarity is required lead salts dominate in electrical applications, and calcium-zinc combinations have been traditionally used when FDA approval is necessary. Organic phosphites are also utilized as so-called chelators, complexing the half-chloride salt... 

Components of fluidized cracking catalysts (FCC), such as an aluminosilicate gel and a rare-earth (RE) exchanged zeolite Y, have been contaminated with vanadyl naphthenate and the V thus deposited passivated with organotin complexes. Luminescence, electron paramagnetic resonance (EPR) and Mossbauer spectroscopy have been used to monitor V-support interactions. Luminescence results have indicated that the naphthenate decomposes during calcination in air with generation of (V 0)+i ions. After steam-aging, V Og and REVO- formation occurred. In the presence of Sn, Tormation Of vanadium-tin oxide species enhance the zeolite stability in the presence of V-contaminants. 

The reaction of butyltin trichloride with l-(2-methyl-2,3-dihydrobenzotriazol-2-yl)-propan-2-one gives an organotin complex that was formulated as containing the [BuSn(OH)Cl3]2 anion " . However, a reinvestigation of the crystal structure of this complex reveals a neutral hydroxyl-bridged aqua-butyldichlorotin hydroxide dimer that is linked to four 2-methylbenzothiazole molecules by short hydrogen bonds " . 

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