Organophosphate poisoning after

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Bloch-Shilderman, E., Kadar, T., Levy, A., Sahar, R., Rabinovitz, I., Gilat, E. (2005). Subcellular alterations of protein kinase C isozymes in the rat brain after organophosphate poisoning. J. Pharmacol. Exp. Ther. 313 1082-9. 

Arima H, Sabue K, So M, Morishima T, Ando H, Katsuya H. Transient and reversible parkinsonism after acute organophosphate poisoning. J Toxicol Clin Toxicol 2003 41 67-70. 

Kupfermann N, Schmoldt A, Steinhart H. Rapid and sensitive quantitative analysis of alkyl phosphates in urine after organophosphate poisoning. J Anal Toxicol 2004 28 242-8. 

Glasgow scale E2M4V2) with profuse oral secretions, sweating, cyanosis, muscle fasciculations and convulsions, and was intubated. Organophosphate poisoning was not suspected at first, and he was treated with dopamine and isoprenaline to increase blood pressure and heart rate and with phenytoin to control the convulsions, but all of these treatments were without effect. At 3.5 h after exposure, he was treated with 2 mg IV of atropine, which immediately increased both heart rate and blood pressure, and 10 mg IV of diazepam, which controlled the convulsions. He was maintained on continuous IV atropine (3 mg day-1) and mechanical ventilation, and 9 days after exposure he became alert and was extubated. The authors stressed the importance of systemic atropine for treating the bradycardia produced by the VX. 

Warnick SL, Carter JE Some findings in a study of workers occupationally exposed to pesticides. Arch Environ Health 25 265-270,1972 White RF, Feldman RG, Proctor SP Neurobehavioral effects of toxic exposures, in Clinical Syndromes in Adult Neuropsychology The Practitioner s Handbook. Edited by White RF. Amsterdam, Elsevier, 1992, pp 1-51 Whorton MD, Obrinsky DL Persistence of symptoms after mild to moderate acute organophosphate poisoning among 19 farm field workers. J Toxicol Environ Health 11 347-354, 1983... 

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Rivett. K.. and Poigieier, P. D, (1987). Diaphragmatic paralysis after organophosphate poisoning. SMAT72, 881-882. 

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Dillard M, Webb J. Administration of succit lcholine for electroconvulsive therapy after organophosphate poisoning a case study. AANA J (1999) 67,513-17. 

C. Bronchoconstriction and secretion and muscular weaknesses occur from acetylcholine accumulation after inhibition of acetylcholinesterase. Parathion is an organophosphate insecticide that inhibits acetylcholinesterase, and it is readily available. Poisoning with compound 1080 (fluorocitrate) inhibits mitochondrial respiration and causes seizures and car-... 

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