Optimization audits

However, many of these tools, while enabling markedly faster and more detailed analysis than paper-based methods, still mimic static, one-by-one paperlike reports with no real-time auditing capability. Moreover, these COTS do not have integrated data analysis and automated data screening capabilities and are not optimized for systematic analyses. Furthermore, the ad hoc analyses that these COTS produce lack interactive, automatic auditing reproducible functions. Thus these tools are often used to produce the same dense, unwieldy paper tables of counts and percentages that were created manually before personal computers became ubiquitous. 

Herbst et al.2 described automated high-throughput ADME/Tox profiling for optimization of preclinical candidates, a Profiling Toolkit enables researchers to request profiles, track progress, receive notification when the requests have been filled, and view data. Automated systems and bar coding improve efficiency, help track compound and plate locations, and create audits trail of the profiling process. 

It will become clear that the major goal of therapy is to reduce low-density lipoprotein (LDL) cholesterol with the statin class of drugs. Sadly, audit data point to the fact that many patients are not yet receiving optimal management. 

Governments receive the public s tax, so they have a responsibility to protect the public interest. Due to safety and public properties of the external effect , it is difficult for the market mechanism to achieve optimal allocation of resources in mine safety production the public began to demand the government from the perspective of the public interest for the mine production safety management. Safety responsibility will be the government s fiduciary duty. It is entrusted with the responsibility to expand the field of mine safety. Safety audit will become an important element of the audit. 

Manual techniques such as reviews, walk-throughs, inspections or audits should be applied to the verification of all life cycle phases and they may be the only applicable technique for verification of those phases which precede source code generation. Since these are manual methods it is important that the means by which the results of such reviews are to be recorded is considered. Use can be made of checklists. However, care should be taken in the construction of checklists to optimize their usefulness (for example, the required response to a checklist item should be clear and not open to interpretation). The means by which the verifiers are to record the results of their reviews should be stated in the verification plan together with a justification of the chosen method. 

Note that for circumstances where operational conditions are changing, for instance in a combined oil and gas field where relative volumes of gas, oil, and seawater, as well as molecular wei ts are changing, the two audit types may occur simultaneously if retrofit, optimization, or redesign become an issue. 

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