Optical sensors, description

Design description The transmitter is designed to operate at 2.5 Gb/sec with a NRZ data input format. The elements include housing, electrical interface, optical interface, drive circuitry, temperature control, optical sensors, data buffers, modulator, and attenuator. 

In summary, in this chapter we provided a general overview of the components of an optical sensor system. Specific implementations of the various components of this system have been presented and representative references to detailed descriptions of a number of sensor systems has been provided. The field of optical sensors for biological and chemical sensors continues to grow and remains focused on the development of low power, portable devices. 

Micro-optodes are based on the change of optical properties (fluorescence intensity or fluorescence lifetime) of a layer covering an optical microfiber. Microsensors are developed for O2, pH, and temperature. The presence of the substrate induces quenching of the fluorescence intensity or decrease of the fluorescence lifetime. Klimant et al. (1997) gave a description of the theory and practice of this technique. Advantages of optical sensors are their ease of manufacture, insensitivity to noise, stability of calibration, and mechanical strength. Disadvantages include their size (ca. 20 pm), limited types of sensors available, and cost of the opto-electronics. 

In this chapter we first discuss the fundamentals and the design aspects of an integrated optical YI sensor (Sect. 10.2), followed by a description of the experimental setup (Sect. 10.3). In the result section (Sect. 10.4) both protein and vims detection experiments are discussed. Section 10.5 demonstrates the use of microfluidic chips for efficient sample handling in combination with the YI sensor. This chapter concludes with a discussion on the prospects of the sensor for point-of-care diagnostics. 

One other, very descriptive classification of flow-through sensors is based on the location of the active microzone and its relationship to the detector. Thus, the microzone can be connected (Figs 2.6. A and 2.6.B) or integrated (Fig. 2.6.C) with the measuring instrument. Sensors of the former type use optical or electric connections and are in fact probe sensors incorporated into flow-cells of continuous analytical systems they can be of two types depending on whether the active microzone is located at the probe end (e.g. see [17]) or is built into the flow-cell (e.g. see [18]) — in this latter case. 

This expression is the basic description for the use of the pyroelectric effect in a host of sensor applications including the well known optical detection devices (82,83). A particularly useful way of describing this type of system is with an equivalent circuit where the pyroelectric current generator drives the pyroelectric impedance and the measuring amplifier circuit as shown in Figure 11. 

Fig. 1 Descriptive scheme of the experimental setups for dengue virus detection. (A) Photon counting unit. (Al) Hamamatsu HC135-01 PMT Sensor Module. (A2) PMT fixation ring. (A3) Manual shutter (71430, Oriel). (A4) Fiber holder that prevents the movement of the fiber inside the photon counting unit. (A5) Fiber optic. (A6) Connection wire of PMT to computer. (A7) Electricity cable. (B) The outside handle of manual shutter that enables light access to the PMT. (C) Immobilization unit. (Cl) Fiber optic. (C2) lOOpl pipette tip. (C3) Conical tube cup. (C4) Point of fixation of fiber. (C5) Optical fiber core. (C6) Biorecognition elements according to MAC-ELISA chemiluminescent OFIS (Alias et al. 2009). (C7) Test samples. (E) Connection to computer...

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