Optical imaging oxidization

Annexin V-functionalized crosslinked iron oxide (CLIO) was designed as a contrast agent for MRI, which was additionally labeled with Cy5.5 to allow colocalization with optical imaging techniques [98]. Alternatively, conjugation of multiple Gd-DTPA molecules or SPIO particles to the C2 domain of synaptotagmin I was shown to allow the detection of apoptotic cells in vitro [99]. Zhao et al. [100] were the first to apply a C2 domain-functionalized SPIO and showed very promising results for future in vivo applications of MR contrast agents for the detection of apoptotic sites. 

Figure 14.12 Changes in electrical conductivity o of two-dimensional crystals NbSe2, M0S2 and graphene. Authors instrument (inset) is an optical image of two-dimensional NbSe2 on top of an oxidized silicon wafer (used as a gate electrode) with a set of gold contacts (after [65]).

The earliest non-invasive imaging method for islet grafts is the optical imaging technique based on bioluminescence for visualization of transplanted islets [15]. This bioluminescence imaging (BLI) system utilizes the reaction between luciferase enzymes and luciferin substrates. The luciferase enzyme generates visible light by the oxidation of substrate in the presence of oxygen. The... 

Another approach called optoelectronic tweezers shows great promised for cell sorting. Optoelectronic tweezers use direct optical images to create high-resolution DEP electrodes. The optoelectronic tweezers are constructed by assembling a ground layer (indium tin oxide (ITO)-... 

Figure 9.2 Optical images of graphene oxide water solution in a tube treated at different...

Sumner, J. R Conroy, R. Shapiro, E. M. Moreland, J. Koretsky, A. P. Delivery of fluorescent probes using iron oxide particles as carriers enables in-vivo labeling of migrating neural precursors for magnetic resonance imaging and optical imaging. J. Biomed. Opt. 2007, 12, 051504/1-051504/6. 

Figure 3.40 Phase contrast optical image of a monolayer crystal of poly(ethylene oxide) grown at 55°C in a 10 pm molten film. Edges of the 22 nm thick lamella are revealed by self-decoration after quenching. The 6-axis is vertical and the a -axis is horizontal this shape may be compared with that in Figure 3.9. Width of the micrograph is 150 pm. From Kovacs and Gonthier [57] with kind permission from Springer Science-tBusiness Media B.V.

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