Oligonucleotides drug delivery

Lysik, M.A., and Wu-Pong, S., Innovations in oligonucleotide drug delivery, Journal of Pharmaceutical Sciences, 2003, 92, 1559-1573. 

Lysik MA, Wu-Pong S (2003) Innovations in oligonucleotide drug delivery. J Pharm Sci 92 1559-1573... 

Remaut, K., Lucas, B., Braeckmans, K., Sanders, N. N., De Smedt, S. C. and Demeester, J. (2005). FRET-FCS as a tool to evaluate the stability of oligonucleotide drugs after intracellular delivery. J. Control Release 103, 259-71. 

I. Aynie, C. Vauthier, E. Fattal, and M. Foulquier, Alginate nanoparticles as a noval carrier for antisense oligonucleotides, in Future Strategies for Drug Delivery with Particulate Systems, Stuttgart, 1997, pp. 11-16. 

Fenske DB, Maurer N, Cullis PR. Encapsulation of weakly-basic drugs, anti-sense oligonucleotides and plasmid DNA within large unilamellar vesicles for drug delivery applications. In Torchilin VP, Weissig V, eds. Liposomes A Practical Approach. 2nd ed. Oxford Oxford University Press, 2002, Chapter 6. 

In view of the preferential distribution of some AS-ODNs to the kidney the oligonucleotide backbone could even be employed for renal-specific drug delivery because of both their intrinsic activity and the potential of coupling of other agents to them. 

Vinogradov, S., Batrakova, E. and Kabanov. A. (1999b) Poly(ethylene glycol)-polyethyleneimine NanoGel particles novel drug delivery systems for antisense oligonucleotides. Colloids and Surfaces B Biointerfaces, 16, 291-304. 

Merdan, T., Kopecek, J., and Kissel, T. (2002) Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. Adv. Drug Delivery Rev. 54, 715-758. 

Aynie IC, Vauthier C, Fattal E, Foulquier M, Couvreur P (1998) Alginate nanoparticles as a novel carrier for antisense oligonucleotide. In Diederichs JE, Muler R (eds), Future Strategies of Drug Delivery with Particulate Systems. Stuttgart Medipharm Scientific Publisher, pp 5-10... 

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