Offspring

Crossover, which is also called recombijiation, follows the idea that aji offspring in natiu c always holds genes from both its parents. Accordingly, the genetic crossover operator takes parts of two parent chromosomes to create a new offspring. 

Symptoms of deficiency in animals include poor appetite, stunted growth, and weight loss increased incidence of irritabihty and convulsions (tetany) some growth abnormahties decreased egg production in poultry with reduced hatchabihty and thin eggsheU quahty and birth of weak, dead, or deformed offspring in other animals. 

It was agreed at the workshop that endocrine disrupting activity could only be adequately defined in terms of effects in intact animals, be they juvenile or adult, or in the offspring of exposed parents. For many chemicals, evidence of endocrine disrupting activity has been obtained only by the use of in vitro models, such as hormone binding assays. It was accepted, therefore, that chemicals active in such models should be considered only as potential EDs and should be distinguished from those established as active in vivo. For such chemicals, an alternative definition was recommended ... 

Culture a range of invertebrate species from the major phyla, preferably species with short life cycles. The effects of potential endocrine disrupting chemicals on growth rate, reproductive output, viability of offspring and sex ratio, and the vulnerability of different stages of the life cycle, can then be determined. 

Mutation is allowed to oeeur in some of the offsprings, the amount being eon-trolled by the mutation rate, typieally a very small number. This results in the random ehange in a gene in an offspring, i.e. from 0 to 1. 

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