Cluster 9 Brain Cancers in Offspring of Electronics Workers

6 Cluster 9 Brain Cancers in Offspring of Electronics Workers 

A unique cancer cluster was reported in which children of parents (both mothers or fathers) who worked at the same electronics manufacturing plant developed intracranial neoplasms.I12 Parents were exposed to some 30 different chemical classes containing more than 100 different compounds. These compounds included 

Despite the large number of lipophiles and hydrophiles to which these workers were exposed, only one cancer type was reported, in offspring only, and no unusual cancer prevalences were identified for the exposed workers. 

The three cancer clusters just discussed are interesting to analyze. Two different sets of chemical mixtures (in electronics workers and petrochemical workers) induced brain cancers in those exposed, whereas in one instance (the second electronics worker group) only the children of those exposed developed brain cancer. These studies show that different mixtures of chemicals can induce the same cancer types and that different mechanisms are at work in the development of the same cancer type. In all three clusters, none of the individual chemicals that the workers were exposed to is known to be causative for brain cancer. 

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Cluster 1 Childhood Leukemia 468 Cluster 2 Prostate Cancer 468 Clusters 3-6 Testicular Cancer 469 Cluster 7 Brain Cancer Cluster—Electronic Workers 469 Cluster 8 Brain Cancer Cluster—Petrochemical Workers 470 Cluster 9 Brain Cancers in Offspring of Electronic Workers 470 Cluster 10 Kidney Cancer Cluster 471 Cluster 11 Colorectal Cancer Cluster 471 Cluster 12 Multiple Cancer Cluster 471 Cluster 13 Lung Cancer Cluster 472 Cluster 14 Childhood Leukemia 472 Cluster 15 Multiple Cancer Clusters 473 Cluster 16 Toxic Waste Disposal Site-Related Clusters 474... 

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