Of oleanolic acid

Matsuda H, Dai Y, Ido Y, et al. Studies on Kochiae fiructus. V. Antipruritic effects of oleanolic acid glycosides and the structure-requirement. Biol Pharm Bull 1998 21 1231-1233. 

Table 8. Antiviral activity of oleanolic acid derivatives 32-37 against HRV-IB and VSV infection.

Balanehru S, Nagarajan B. Protective effect of oleanolic acid and ursolic acid against lipid peroxidation. Biochemistry International 1991 24 981-990. 

The reported partial synthesis of oleanolic acid from jS-amyrin (see Vol. 1, p. 193) has been re-examined.It has been established by deuterium labelling studies that epoxidation of /3-amyrin acetate with m-chloroperbenzoic acid gives the 12a,13a-epoxide and not the 12)8,13/3-epoxide as previously suggested. It follows, therefore, that the compound synthesized in the original work was the lactone (124), erroneously identified as oleanolic lactone acetate. Unexpectedly,... 

An inhibitory effect against VSV multiplication was observed for five oleanolic acid glycosides from Calendula arvensis while rhinovirus (HRV) replication was significantly affected by only one compound, a bidesmosidic triglycoside of oleanolic acid [157],... 

Hsu, H.Y Tsai, M S. The investigation of oleanolic acid and ursolic acid combined with high dose ionizing radiation on the apoptosis of HL-60 cells. Cancer detection and Prevention Online. 2000, 24 (Supplement 1). 

To expand our understanding of the anti-inflammatory activity of the well-known oleanolic acid isolated from one of its best characterised sources, the seeds of Luffa cylindrica (Cucurbitaceae), a series of experiments were performed to correlate complement activity with the inflammation caused by both carrageenan and Freund s adjuvant, in presence and absence of oleanolic acid and ibuprofen, which were administered at 60 mg/kg i.p. It was concluded that the effect of this triterpenoid must be mediated by its anti-complementary activity 73]. An analogous conclusion was drawn regarding the activity of boswel ic acids in the same tests [74]. 

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