Oestrogen replacement therapy

MacLennan A, Lester S, Moore V (2004) Oral oestrogen replacement therapy versus placebo for hot flushes (Cochrane Review). In The Cochrane Library, Issue 1. Wiley, Chichester... 

Ethinyloestradiol Synthetic oestrogen Used for oestrogen replacement therapy in deficient states, both pre- and postmenopausal. Treatment of prostate cancer (male), breast cancer (post-menopausal women). Component of many oral contraceptives... 

Oestradiol Natural oestrogen Oestrogen replacement therapy in menopausal, post-menopausal or menstrual disorders. Management of breast cancer in post-menopausal women and prostate cancer in man... 

Thorneycroft IH. The role of oestrogen replacement therapy in the prevention of osteoporosis. Am. J. Obstet. Gynecol. 160, 1306-1310, 1989. 

Oestrogen replacement therapy (see Post-menopausal oestrogen therapy)... 

Scarabin PY, Oger E, Plu-Bureau GEStrogen and THromboEmbolism Risk Study Group. Differential association of oral and transdermal oestrogen-replacement therapy with venous thromboembolism risk. Lancet 2003 362(9382) 428-32. 

Erkkola R, Holma P, Jarvi T, Nummi S, Punnonen R, Raudaskoski T, Rehn K, Ryynanen M, Sipila P, Tunkelo E et al. (1991) Transdermal oestrogen replacement therapy in a Finnish population. Maturitas 13 275-281... 

Q17 There are some major problems associated with oestrogen-replacement therapy. These include pulmonary embolism, thromboembolism, seizures, hepatic adenoma and risk of stroke. There is also now evidence of an increased incidence of breast, ovarian and endometrial cancer, which is related to the duration of HRT use. Approximately 14 in every 1000 women aged 50-64 years not using HRT develop breast cancer. Use of oestrogen-only HRT for five years in this age group increases the incidence of breast cancer to about 15.5 in every 1000 women this represents a relatively small increase in risk. 

Oestrogen replacement therapy, a good treatment for prevention of osteoporosis. It is not recommended unless there are other indications for its nse as well. There is nncertainty and controversy about whether oestrogen shonld be recommended in women in the first decade after the menopause. 

Ranganath LR, Christolides J, and Semple MJ. (1996). Increased mean platelet volume after oestrogen replacement therapy. Annals Clin. Biochem. 33 ( Pt 6), 555-560. 

NSC 12169 Ortho-Gynest Ovestin and many other names) is a naturally occurring steroid, an OESTROGEN that is used orally or topically in oestrogen replacement therapy (sometimes in combination with a PROGESTOGEN) to treat menstrual, menopausal or other gynaecological problems (including infertility), oestriol succinate oestriol. 

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