Octane 2-chloro

Octane, 1-bromo-, 55,111 Octane, 1-chloro-, 55,111 Octane, 1-iodo-, 55, 105, 111 Octane, 2-methyl-, 112 Octane, 1 tosyl- [Octane, l-(4-methylphenyl-sulfonyl) ], 55,111... 

Capryl chloride 1-Chlorooctane EINECS 203-915-5 HSDB 5551 NSC 5406 Octane, 1-chloro- Octyl chloride 1-Octyl chloride n-Octyl chloride. Liquid mp = -57.8° bp = 181.5° d = 0.8738 insoluble in H2O, slighlly soluble in CCU, very soluble in EtOH, EtzO. 

Octanecarboxylic acid. See Nonanoic acid 1-Octane, 1-chloro-. See Octyl chloride 1,8-Octanedicarboxylic acid Octane-1,8-dicarboxylic acid. See Sebacic acid Octane, 1,1-dimethoxy-. SeeOctanal dimethyl acetal... 

CAS 111-85-3 EINECS/ELINCS 203-915-5 Synonyms Capryl chloride Caprylic chloride Caprylyl chloride 1-Chlorooctane 1-Octane, 1-chloro-... 

This has been confirmed by Spath and Lorenz, who have shown that dihydro-0-conhydrinemethine must be a-dimethylamino-octan-j8-ol, MejN. CHj. CHOH. CHa. (CHa). CHj, since it is oxidised by chromic acid in acetic acid to a-dimethylamino-octan-(3-one, which has been synthesised from w-heptoylchloride by the action of diazomethane in ether, and treatment of the resulting a-chloro-w-octan-(3-one with dimethylamine. 

Because the Williamson synthesis is an S 2 reaction, it is subject to all the usual constraints, as discussed in Section 11.2. Primary halides and tosylates work best because competitive E2 elimination can occur with more hindered substrates. Unsymmetrical ethers should therefore be synthesized by reaction between the more hindered alkoxide partner and less hindered halide partner rather than vice versa. For example, terf-butyl methyl ether, a substance used in the 1990s as an octane booster in gasoline, is best prepared by reaction of tert-butoxide ion. with iodomethane rather than by reaction of methoxide ion with 2-chloro-2-methylpropane. 

Bicyclo[2.2.1]hepta-2,5-diene, nitrosyl chloride adduct, 46, 74 reaction with acetic acid to yield nortricyclyl acetate, 46, 74 Bicyclohexyl, 46, 61 Bicyclohexylidene, 47, 34 ejSO-e s-BlCYCLO[3.3.0]OCTANE-2-CAR-BOXYLIC ACID, 47, 10 Bicyclopentadienylidene, octa-chloro-, 46,93... 

Scheme 54 Synthesis of (2/t,55)-l,3-diaza-2-chloro-3-phenyl-2-phosphabicyclo[3.3.0]octane 198...

A number of 1,3,2-diazaphospholidinc derivatives 264-265 having (5S)-1,3-diaza-2-phospha-2-oxo-3-phenylbicyclo[3.3.0]octene moiety (labeled as P) were prepared using diastereomerically pure (5.S)-1,3-dia/a-2-chloro-2-phospha-2-oxo-3-phenylbicyclo[3.3.0]octane (263) as a key substrate. Its preparation was in turn based on the reaction of phosphoryl chloride with (-)-197 (Scheme 63) [96-100]. 

The parent compound, 69, has been synthesized and characterised <2003ZFA1475>. 4-Chloro-hepta-l,6-diene was reacted with Mg. No Grignard rearrangement was noticed but instead the Grignard reagent was converted into l-allyl-3-butenylphosphonous dichloride by reaction with PC13. Reduction with LiAlH. produced l-allyl-3-butenyl-phosphane. Radical-initiated cyclization led to the product, l-phosphabicyclo[3.3.0]octane. Four derivatives were similarly prepared and characterized (70-73). Compound 74 was similarly prepared via a radical reaction < 1997PS(123)141 >. 

Nonanoate/trifluo-rohexanoate or nonafluorononano-ate or tridecafluo-rodecanoate Octaoate/1 -chloro-octane... 

These results were explained by the discovery that the chloro-ruthenium complexes are not the primary photoproducts under CO in 1.0 M CCl /octane solution. Instead Ru(CO>5 proved to be the initial product even after nearly complete photofragmentation of the starting material, and the chlorocarbonyl ruthenium products to be the result of a secondary, dark reaction between the Ru(C0)5 and CCI4 (3) ... 

Table 7. 2-Alkoxy-6-oxotricyclo [3.2.1.0] octane-1-carboxylates 83 from alkoxycyclohexadienolates 82 and methyl 2-chloro-2-cycIopropylideneacetate (4), and their transformation to 2,6-dioxobicyclo-[3.2.1]octane-l-carboxylates 84 [26,15]...

A similar reaction of 1,5-cyclooctadiene with trichloromethyl radicals, produced from carbon tetrachloride and dibenzoyl peroxide, leads to 2-chloro-6-trichloromethylbicyclo-[3.3.0]octane (94), with chloroform and dibenzoyl peroxide the analogue 95 is obtained and iV-t-butylfonnamide affords compound 96 (equation 57)62,63. 

The first carbon atom in both the cases is exactly identical and difference arises from the second carbon. This carbon has two other carbon atoms attached to it in isobutyl whereas the analogous carbon in normal butyl has only one attached carbon. Therefore, isobutyl gets precedence over normal butyl. On this basis, the following configuration of 4-chloro 2 methyl octane would be S... 

An E2 mechanism has been proposed to account for the kinetics of formation of 3-azabicyclo[3.3.0]oct-2-ene on dehydrohalogenation of Al-chloro-3-azabicyclo[3.3.0]octane in alkaline medium. ... 

The Michael addition followed by Intramolecular Ring Closure (MIRC) reactions have been recognized as a general synthetic approach to carbocyclic three-membered ring derivatives [1]. The enhanced Michael reactivity of methyl 2-chloro-2-cyclopropylideneacetate (1-Me) towards thiolates, alkoxides, lithiated amides and cyclohexadienolates (see below) allows one to perform highly efficient assemblies of spiropentane, tricyclo [3.2.1.0 ]octane, bicyclo [2.2.2] octane... 

Acetonitrile, phenyl-, 55,91, 94 Acetonitrile-18-crown-6 complex, 57, 31 Acetophenone, 58, 57, 61 ACETOPHENONE, 2-(2-ACETAMIDO-ETHYLE4,5-DIMETHOXY-, 56, 3 Acetophenone, 2-(2-acetamidoethyl)-4,5, 6-trimethoxy-, 56, 7 Acetophenone, 4-chloro, 55, 40 Acetophenone, 4-chloro-, oxime, 55, 39, 40 7-Acetoxy-4,4,6,7-tetramethylbicyclo-[4 2 0] octan-2-one, 57, 113 Acctylacetone, 58, 52, 56 Acetyl chloride, a rert-butyl-o-cyano-, 55, 38... 

A solution of A -(2-chloro-l,l,2-trifluoroethyl)-A, A -diethylamine (2 16.2 g, 0.085 mol) in anhyd Et20 (10 mL) was added dropwise to a solution of (+)-(S)-octan-2-ol (3 10 g, 0.077 mol) in anhyd Et20 (10 mL) cooled at 0 C. The mixture was allowed to stand at 0°C for a further 24 h and was then washed with sat. aq NaHC03 and H20 until neutral. The organic layer was dried (MgSOJ, concentrated, and distilled (bulb-to-bulb. 15Torr, bath temperature 50CC) into a receiver cooled to —75°C. The volatile products were treated with Br2 and redistilled (bulb-to-bulb, 0.01 Torr, rt) to afford ( — )-(/ )-2-fluorooctane (4) yield 4.5 g (44%). 

A mixture of silver(I) fluoride and 2,2 -bipyridine replaces chlorine with fluorine in 1-chloro-octane in 86% yield after 45 minutes at 130°C.28 Some heterocyclic polychloro derivatives are also fluorinatcd by silver(I) fluoride. Thus, perfluoro(2,3,4,5-tetrahydropyridine) (1) and per-fluoro(3,4-dihydro-2//-pyrrole) are prepared from 2,2,6-trichloro-3,3,4,4,5,5-hexafluoro-2,3.4,5-tetrahydropyridine and 2,2,5-trichloro-3,3,4.4-tetrafluoro-3,4-dihydro-2//-pyrrole by reaction with silver(l) fluoride at room temperature.31 Since the fluorination of 2,2,5-trichloro-3,3,4,4-tetrafluoro-3,4-dihydro-2//-pyrrole with silver(l) fluoride is slow, recycling is necessary.31... 

LXXVIII a (R)-3,7-Di- methyl- octanal-di- vinylacetal l34h26u2 226,4 Chloro- form 10,703 26 589 + 3,04 ... 

Magnesium-mediated elimination of bromine monofluoride has been reported in the reaction of 2-bromo-2-chloro-l,l,l-trifluoroethane with ketones, e.g. reaction of 5 with octan-2-one. 

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