3-O-P-D-glucuronide

N.A. 3-O-P-D-glucuronide, mucilage, tannins, flavones.103117 Treat skin irritation and bums, infused flower for gargle for sore throat and laryngitis. It is anti-irritant and used as a mild sun screen, inhibiting microbial growth. 

Day et al. [2001] detected >20 species of metabolites, including quercetin 3-O-p-D-glucuronide (Q3GA), quercetin 3 -0-(3-D-glucuronide (Q3 GA), quercetin... 

Bouktaib M, Atmani A, Rolando C (2002) Regio- and stereoselective synthesis of the major metabolite of quercetin, quercetin-3-O-P-d-glucuronide. Tetrahedron Lett 43 6263-6266... 

Figure 18 Variation of log P as a function of folding in morphine-3-O-p-D-glucuronide, as quantified by the distance between the 6-OH group of morphine and the COOH group d glucuronic acid. (Ref. 56.)...

The distribution of the two morphine glucuronides, morphine-3-O-p-D-glucuronide (M3G) and morphine-6-O-p-D-glucuronide has been... 

Kaempferol, kaempferol-3-O-P-D-galactopyranoside kaempferol-3-O-P-D-rutinoside (nicotiflorin), quercetin, quercetin-3-0-P-D-glucuronide methyl ester, quercetin-3-O-P-D-glucopyranoside (isoquercitrin), quercetin-3-O-P-D-galactopyranoside (hyperoside)... 

Epicatechin-O-p-D-glucuronide 3 [M—Glucuronic acid-hHH (100) [ A -i-Glucuroiiic acid] (35)... 

Pfaar, U. Gygax, D. Gertsch, W. Winkler, T. Ghisalba, O. (1999) Enzymatic synthesis of p-D-glucuronides in an enzyme membrane reactor. Chimia, 53, 590-3. 

D.-M. He, I. Kaleem, S.-Y. Qin, D.-Z. Dai, G.-Y. Liu, C. Li, Biosynthesis of glycyrrhetic acid 3-O-mono-P-D-glucuronide catalyzed by p-D-glucuronidase with enhanced bond selectivity in an ionic liquid/buffer biphasic system. Process Biochem. 45 (2010) 1916-1922. 

T. Kuramoto, Y. Ito, M. Oda, Y. Tamura, S. Kitahata, Microbial production of glycyrrhetic acid 3-O-mono-p-D-glucuronide from glycyrrhizin by Cryptococcus magnus MG-27, Biosci. Biotechnol. Biochem. 1994. 58,455-458. 

Figure 3 Structures of (A) hypericin (B) pseudohypericin (C) hyperforin (D) flavo-noids (R=H quercetin R=a-L-rhamnosyl quercitrine R=P-D-glucosyl isoquerci-trine R=P-D-galactosyl hyperoside R=P-D-rutinosyl rutin R=P-o-glucuronide miquelianin) and (E) procyandin B2.

Figure 4.3 Chemical structures of Isoflavone glycosides. In soy foods, Isoflavones form 7-0-P-glucosIde conjugates. A Is the simple glucoside commonly found In soy milk, B Is the 6"-0-malonyl-7-0-p-glucoslde from the soybean, and C Is the 6"-0-acetyl-7-O-p-glucoside, a product of toasting of soy flour. D is the 7-0-P-glucuronide that is the principal conjugate in the blood.

Details of the selective cleavage of o-glucuronidic linkages in saponins have been published (see Vol. 10, p. 117). A modified procedure for determining the sites of attachment of hexuronic acid residues in methylated acidic polysaccharides by base-catalysed degradation has been modelled on experiments with the methylated aldobiouronic acid derivative (430), which eliminated methyl 2,3,4-tri-O-methyl-p-D-glucopyranoside (89%) on treatment with sodium methylsulphinyl-methanide in DMSO at room temperature. When this procedure is applied to... 

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