Nurrl

Hering, R., Petrovic, S., Mietz, E. M. et al. Extended mutation analysis and association studies of Nurrl (NR4A2) in Parkinson disease. Neurology 62 1231-1232, 2004. 

Parkinson s Synuclein, parkin, UBCH1, Nurrl Enzyme TH, GTPCH, AADC Growth factor GDNF Local Striatum Kang et al. (1993) Leff et al. (1999) Sanchez-Pernaute et al. (2001) Kirik et al. (2002) Muramatsu et al. (2002)... 

Kim SY, Choi KC, Chang MS, Kim MH, Kim SY, et al. 2006. The dopamine D2 receptor regulates the development of dopaminergic neurons via extracellular signal-regulated kinase and Nurrl activation. J Neurosci 26 4567-4576. 

Xing G, Zhang L, Russell S, Post R. 2006. Reduction of dopamine-related transcription factors Nurrl and NGFI-B in the prefrontal cortex in schizophrenia and bipolar disorders. Schizophr Res 84 36-56. 

Backman C, You ZB, Perlmann T, Hoffer BJ (2003) Elevated locomotor activity without altered striatal dopamine contents in Nurrl heterozygous mice after acute exposure to methamphetamine. Behav Brain Res 743 95-100. 

Le W, Conneely OM, He Y, Jankovic J, Appel SH (1999a) Reduced Nurrl expression increases the vulnerability of mesencephalic dopamine neurons to MPTP-induced injury. J Neurochem 73 2218-2221. 

Le WD, Conneely OM, Zou LL, He Y, Saucedo-Cardenas O, Jankovic J, Mosier DR, Appel SH (1999b) Selective agenesis of mesencephalic dopaminergic neurons in Nurrl-deficient mice. Exp Neurol 759 451-458. 

Saucedo-Cardenas O, Quintana-Hau JD, Le WD, Smidt MP, Cox JJ, DeMayo F, Burbach JPH, Conneely OM (1998) Nurrl is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons. Proc Natl Acad Sci USA 95 4013 1018. 

Zetterstrom RH, Solomin L, Jansson L, 11 offer BJ, Olson L, Perlmann T (1997) Dopamine neuron agenesis in Nurrl-deficient mice. Science 276 248-250. 

Sacchetti P, Mitchell TR, Granneman JG, Bannon MJ (2001) Nurrl enhances transcription of the human dopamine transporter gene through a novel mechanism. J Neurochem 76 1565-1572. 

NGFI-B and the Nurrl ligand-binding domain. J. Biol. Chem. 2005 280 19250-19258. 53. 

Wang Z, et al. Structure and function of Nurrl identifies a class of... 

Schmidt CJ. Decreased expression of the transcription factor NURRl in dopamine neurons of cocaine abusers. Proc Natl Acad Sci USA 2002 99(9) 6382-5. 

Tetradis, S., Bezouglaia, O. and Tsingotjidou, A. (2001) Parathyroid hormone induces expression of the nuclear orphan receptor Nurrl in bone cells. Endocrinology, 142, 663-670. 

Zetterstrom, R.H., Solomin, L., Mitsiadis, T., Olson, L. and Perlmann, T. (1996) Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurrl, and... 

Paulsen, R.F., Granas, K., Johnsen, H., Rolseth, V. and Sterri, S. (1995) Three related brain nuclear receptors, NGFI-B, Nurrl, and NOR-1, as transcriptional activators. Journal of Molecular Neuroscience, 6, 249—255. 

Nsegbe, E., Wallen-Mackenzie, A., Dauger, S., Roux, J.C., Shvarev, Y., Lagercrantz, H., Perlmann, T. and Herlenius, E. (2004) Congenital hypoventilation and impaired hypoxic response in Nurrl mutant mice. 

Sakurada, K., Ohshima-Sakurada, M., Palmer, T.D. and Gage, F.H. (1999) Nurrl, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain. Development (Cambridge, England), 126, 4017-4026. 

Bergsland, M., Joodmardi, E. and Perlmann, T. (2006) Neuropilinl is a direct downstream target of Nurrl in the developing brain stem. Journal of Neurochemistry, 97, 1403—1411. 

Hermanson, E., Joseph, B., Castro, D., Lindqvist, E., Aarnisalo, P., Wallen, A., Benoit, G., Hengerer, B., Olson, L. and Perlmann, T. (2003) Nurrl regulates dopamine synthesis and storage in MN9D dopamine cells. Experimental Cell Research, 288, 324-334. 

Castro, D.S., Arvidsson, M., Bondesson Bohn, M. and Perlmann, T. (1999) Activity of the Nurrl carboxyl-terminal domain depends on cell type and integrity of the activation function 2. The Journal of Biological Chemistry, 274, 37483—37490. 

Maheux, J., Efhier, I., Rouillard, C. and Levesque, D. (2005) Induction patterns of transcription factors of the nur family (nurrl, nur77, and nor-1) by typical and atypical antipsychotics in the mouse brain implication for their mechanism of action. The Journal of Pharmacology and Experimental Therapeutics, 313, 460-473. 

Ordentlich, P., Yan, Y., Zhou, S. and Heyman, R.A. (2003) Identification of the antineoplastic agent 6-mercaptopurine as an activator of the orphan nuclear hormone receptor Nurrl. The Journal of Biological Chemistry, 278, 24791-24799. 

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