Nuclear magnetic resonance detection

J. F. Haw, T. E. Glass, and H. C. Dorn, Analysis of coal conversion recycle solvent by liquid chromatography with nuclear magnetic resonance detection. Anal. Chem. 53 (1981), 2332-2336. 

R165 K. Holtin and K. Albert, The Use of Nuclear Magnetic Resonance Detection of LC in Carotenoid Analysis , in Carotenoids Physical, Chemical, and Biological Functions and Properties, ed. J. T. Landrum, CRC Press, Boca Raton, Fla., 2010, p. 61. 

Blechta V, Kurfurst M, Sykora J, Schraml J. High-performance liquid chromatography with nuclear magnetic resonance detection applied to organosilicon polymers. Part 2. Comparison with other methods. J Chromatogr A 2007 1145 175-82. 

Eaton HL, Wyss DF (2011) Effective progression of nuclear magnetic resonance-detected fragment hits. Methods Enzymol 493 447-168... 

Nuclear magnetic resonance of protons was first detected in 1946 by Edward Purcell (Harvard) and by Felix Bloch (Stanford) Purcell and Bloch shared the 1952 Nobel Prize in physics... 

The section on Spectroscopy has been retained but with some revisions and expansion. The section includes ultraviolet-visible spectroscopy, fluorescence, infrared and Raman spectroscopy, and X-ray spectrometry. Detection limits are listed for the elements when using flame emission, flame atomic absorption, electrothermal atomic absorption, argon induction coupled plasma, and flame atomic fluorescence. Nuclear magnetic resonance embraces tables for the nuclear properties of the elements, proton chemical shifts and coupling constants, and similar material for carbon-13, boron-11, nitrogen-15, fluorine-19, silicon-19, and phosphoms-31. 

The presence of iminium salts can be detected by chemical means or by spectroscopic methods. The chemical means of detecting iminium salts are reactions with nucleophiles and are the subject of this review. The spectroscopic methods are more useful for rapid identification because with the large number of model compounds available now the spectroscopic methods are fast and reliable. The two methods that are used primarily are infrared and nuclear magnetic resonance spectroscopy. Some attempts have been made to determine the presence of iminium salts by ultraviolet spectroscopy, but these are not definitive as yet (14,25). 

For a discussion of the use of polarography and nuclear magnetic resonance spectroscopy to detect covalent hydration, see the following... 

Nuclear magnetic resonance, NMR (Chapter 13 introduction) A spectroscopic technique that provides information about the carbon-hydrogen framework of a molecule. NMR works by detecting the energy absorptions accompanying the transitions between nuclear spin states that occur when a molecule is placed in a strong magnetic field and irradiated with radiofrequency waves. 

Porphyrin is a multi-detectable molecule, that is, a number of its properties are detectable by many physical methods. Not only the most popular nuclear magnetic resonance and light absorption and emission spectroscopic methods, but also the electron spin resonance method for paramagnetic metallopor-phyrins and Mossbauer spectroscopy for iron and tin porphyrins are frequently used to estimate the electronic structure of porphyrins. By using these multi-detectable properties of the porphyrins of CPOs, a novel physical phenomenon is expected to be found. In particular, the topology of the cyclic shape is an ideal one-dimensional state of the materials used in quantum physics [ 16]. The concept of aromaticity found in fuUerenes, spherical aromaticity, will be revised using TT-conjugated CPOs [17]. 

Rycroft et al. (1999) identihed the major components of plants from six locations in western Scotland and four from the Azores using nuclear magnetic resonance (NMR) fingerprinting and GC-MS. The terpene P-phellandrene [129], which may be responsible for the aroma of material crushed in the held, was detected in all specimens. The major components, which appear in Fig. 5.6, were shown to be methyl eveminate [444], the four methyl orcellinate derivatives [445 8], the two 9,10-dihydrophenanthrene derivatives [449] and [450], the newly described phthalide killamiensolide [451], and the bibenzyl [453]. Methyl eveminate was the major compound in all 10 specimens other compounds were more varied in their occurrence. Killamiensolide was not isolated as such but was detected when extracts were acetylated yielding, among other compounds, [452]. The presence of the bibenzyl compound [453] in more than trace amounts in P. killarniensis raises the possibility that it represents contamination from P. spinulosa with which it was growing at the one site. 

Knight CTG, SD Kimade (1999) Silicon-29 nuclear magnetic resonance spectroscopy detection limits. A a/ Chem 71 265-267. 

S. D. Beyea, B. J. Balcom, T. W. Bremn-er, R. L. Armstrong, P. E. Grattan-Bellew 2003, (Detection of microcracking in cementious materials with space resolved 1H nuclear magnetic resonance relaxometry), J. Am. Ceram. Soc. 86 (5), 800-805. 

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