Nonylphenol enzymes

Immobilized enzymes, particularly LAC, have been employed in the degradation of triclosan. The immobilization of LAC from Coriolopsis polyzona through the formation of cross-linked enzyme aggregates (CLEAs) and their subsequent use in an FBR for the removal of endocrine disrupting compounds [42] produced the complete removal of triclosan, nonylphenol, and bisphenol A (5 mg L-1 each) at a HRT of 150 min. The application of CLEAs in a perfusion basket reactor [43]... 

Mart ianov, A.A., A.V. Zherdev, S.A. Eremin, et al. 2004. Preparation of antibodies and development of enzyme-linked immunosorbent assay for nonylphenol. Int. J. Environ. Anal. Chem. 84 965-978. 

Cespedes, R., K. Skryjova, M. Rakova, et al. 2006. Validation of an enzyme-linked immunosorbent assay (ELISA) for the determination of 4-nonylphenol and octylphenol in surface water samples by LC-ESI-MS. Talanta 70 745-751. 

Tsutsumi Y, Haneda T, Nishida T (2001) Removal of estrogenic activities of bisphenol A and nonylphenol by oxidative enzymes from lignin-degrading basidiomycetes. Chemosphere 42 271-276... 

Lee JS, Obach RS, Fisher MB (eds) Drug metabolizing enzymes, cytochrome P450 and other enzymes in drug discovery and development. Marcel Dekker, NewYork Lee PC, Marquardt M, Lech JJ (1998) Metabolism of nonylphenol by rat and human microsomes. Toxicol Lett 99 117-126... 

Arukwe, A., L. Forlin and A. Gokspyr. Xenobiotic and steroid biotransformation enzymes in Atlantic salmon (Salmo salar) liver treated with an estrogenic compound, 4-nonylphenol. Environ. Toxicol. Chem. 16 2576-2583, 1997. 

Sturm, A., J.P. Cravedi, E. Perdu, M. Baradat and H. Segner. Effects of prochloraz and nonylphenol diethoxylate on hepatic biotransformation enzymes in trout a comparative in vitrolin vivo-assessment using cultured hepatocyte. Aquat. Toxicol. 53 229-245, 2001. 

Thibaut, R., L. Debrauwer, E. Perdu, A. Gokspyr, J.P. Cravedi and A. Arukwe. Regio-specific hydroxylation of nonylphenol and the involvement of CYP2K- and CYP2M-like iso-enzymes in Atlantic salmon (Salmo salar). Aquat. Toxicol. 56 177-190, 2002. 

Aly HA, Domenech O, Banjar ZM (2012) Effect of nonylphenol on male reproduction analysis of rat epididymal biochemical markers and antioxidant defense enzymes. Toxicol Appl Pharmacol 261(2) 134-141... 

Enzyme-based biosensors have been used also for the detection of phenolic estrogens. The detection principle was based on the ability of tyrosinase to catalyze the oxidation of phenolic estrogens to o-diphenol and o-quinone. Using this principle tyrosinase-carbon paste electrodes have been used for the detection of phenol, catechol, bisphenol A, genistein, quercetin, nonylphenol, and diethylstilbestrol with detection levels in the micromolar range.Optical and amperometric biosensors based on estrogen receptors have also been developed. 

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