Nonaqueous capillary electrophoresis applications

Cherkaoui, S., Varesio, E., Christen, P., and Veuthey, J. L. (1998). Selectivity manipulation using nonaqueous capillary electrophoresis. Application to tropane alkaloids and amphetamine derivatives. Electrophoresis 19, 2900—2906. 

Carabias-Martinez, R., E. Rodriquez-Gonzalo, J. Dominquez-Alvarez, and J. Hemandez-Mendez (2002). Comparative study of separation and determination of triazines by micellar electrokinetic capillary chromatography and nonaqueous capillary electrophoresis Application to residue analysis in natural waters. Electrophoresis, 23 494—501. 

A Karbaum, T Jira. Nonaqueous capillary electrophoresis Application possibilities and suitability of various solvents for the separation of basic analytes. Electrophoresis 20 3396-3401, 1999. 

Nonaqueous capillary electrophoresis is a new technique that matured over the last couple of years to complement the electrophoretic techniques performed under aqueous conditions. Consequently, it extends the applicability of CE to those analytes that are insoluble or only sparsely soluble in water, including several classes of pharmaceutical compounds and long-chain fatty acids, vitamins, and surfactants, to name only a few. 

Yuqin L., Shuya C., Yuqiao C., Xingguo C., Zhide H., Application of nonaqueous capillary electrophoresis for quantitative analysis of quinoUzidine alkaloids in Chinese herbs. Anal. Chim. Acta. 

In this chapter, an overview on the most relevant aspects of the analysis of alkaloids by electromigration methods, namely, capillary zone electrophoresis (CZE), nonaqueous capillary electrophoresis (NACE), micellar electrokinetic chromatography (MEKC), microemulsion electrokinetic chromatography (MEEKC), and capillary electrochromatography (CEC), is given. Selected recent applications of CE in analysis of alkaloids are summarized in a table following the classification according to the chemical nature of the considered compounds. 

The term nonaqueous capillary electrophoresis (NACE) is used to describe the application of pure organic solvents, or their mixtures, in preparation of running buffers for CE experiments. The most important advantages of using nonaqueous miming buffers are (1) the improved solubility of hydrophobic analytes and... 

Wang LJ, Hua SQ, Guo QL, Yang GL, Chen XG. Di-w-amyl L-tartrate-horic acid complex chiral selector in situ synthesis and its application in chiral nonaqueous capillary electrophoresis. J. Chromatogr. A 2011 1218 1300-1309. 

Lister, A.S., Dorsey, J.G., and Burton, D.E., Current measurement of nonaqueous solvents Applications to capillary electrophoresis and electrochromatography,... 

Chiral separations performed with capillary electrophoresis is an ever growing branch in the field of analytical chemistry. More applications originate both in aqueous and in nonaqueous environments, and most likely, cyclodextrins will continue to be the most popular selectors. 

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