2-Nitropropane physical properties

Nitroalkanes are acidic compounds the dissociation of a proton from a nitroalkane produces the nitroalkane anion, or nitronate, whose chemical and physical properties differ from those of the parent nitroalkane. The nitronate form of 2-nitropropane is more mutagenic in S. typhimurium TAIOO and TA 102 than is the neutral parent compound (Fiala et al., 1987b Dayal et al., 1989 Kohl et al., 1994), suggesting that propane 2-nitronate may act as an intennediate in the mechanism by w hich 2-nitropropane exerts its genotoxic and carcinogenic effects. This hypothesis is supported by studies indicating that both bacterial mutagenicity and induction of unscheduled DNA synthesis in rat hepatocytes are decreased by conditions (low pH or deuteration of the secondary carbon atom) that limit formation of the nitronate tautomer, and that the tautomerization of 2-nitropropane can be influenced by hepatic enzymes (Kohl et al., 1994). 

Low-carbon nitroalkanes have similar physical properties as nitromethane, but they are comparatively more difficult to detonate, exhibiting inferior detonation properties, therefore, they are mainly used in liquid explosive mixtures to lower the freezing point of nitromethane. Table 7.1 listed the physical properties of four low-carbon nitroalkanes including nitromethane (NM), nitroethane (NE), o-nitropro-pane, and nitropropane. 

Chemical and Physical Properties The major physical and mechanical properties of poly(caprolactone) are summarized briefly in Table 1.5. Its physical and mechanical properties depend mainly on its molecular weight and crystallinity. In general, aromatic and some polar solvents such as benzene, toluene, cyclohexanone, dichloromethane and 2-nitropropane are good solvents for PCL. Water, alcohols, petroleum ether, diethylether are poor solvents for PCL. PCL can be slightly soluble in acetonitrile, acetone, 2-butanone, ethyl acetate and dimethylformamide. 

The nitroalkanes are named as derivatives of the hydrocarbon with the prefix nitro. The primary or secondary position of the nitro group on propane is indicated by the number 1 or 2. The structure of nitromethane is CH3NO2, CH3CH2NO2 is nitroethane, CH3CH2CH2NO2 is 1-nitropropane, and CH3-CH(N02)CH3 is 2-nitropropane. The CA index names (Chemical Abstract Index, American Chemical Society) for each nitroalkane is listed in Table 17.1 along with the solvent s physical properties. The CAS numbers refer to the major nitroalkane component. Refer to the Material Safety Data Sheet (MSDS) for CAS numbers of any minor impurities in the solvent. 

Physical properties Nitrome thane Nitroe thane 1-Nitropropane 2-Nitropropane Nitrobenzene... 

IR spectrum, 529 physical properties, 536 purification and characterization, 528-529 reaction, 524 synthesis, 524-529 1-nitropropane, 569 5-nitrosalicylic acid, 235,236 purification and characterization, 380-381 reaction, 379 synthesis, 379-381 nitrosamine, 357... 

Nitropropane 49 30 8 Little change in physical property measurements Zytel 101 DuPont... 

Nitropropane 20 5 Limited resistance a higher level of absorbtion occurs resulting in definite loss of physical properties ... 

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