Neurospora crassa, gene mutation test

The gene mutation test in Neurospora crassa US-EPA OPPTS 870.5250... 

The test is used to detect forward and reverse gene mutation in Neurospora crassa, a eukaryotic fungus. These mutations are detected by biochemical or morphological changes in the treated population. The most commonly used mutation assay in Neurospora crassa measures forward mutation in the ad-3 region of the genome. 

Katz, T-M. Ong, A.J.F. Griffiths, and R.S. Stafford. Mutation tests in Neurospora crassa. A report for the U.S. EPA GENE-TOX Program. Mutat. Res. (in press)... 

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