Neural culture

Novelli, A., Kispert, J., Femandez-Smchez, M.T., Torrehlanca, A., and Zitko, N. 1992h. Domoic acid-containing toxic mussels produce neurotoxicity in neural cultures through a synergism between excitatory amino acids. Brain Res 577,41 8. 

De Vellis J, McGinnis JF, Breen GAM, Leveille P, Bennett K, McCarthy K (1977) Hormonal effects on differentiation in neural cultures. In Federoff S, Hertz L (Eds), Cell, Tissue and Organ Cultures in Neurobiology, Academic Press, New York, 485-514. 

Farooqui, A.A., Anderson, D.K., Flynn, C., Bradel, E., Means, E.D., and Horrocks, L.A. (1990) Stimulation of mono- and diacylglycerol lipase activities by bradykinin in neural cultures. Biochemical and Biophysical Research Communications 166 1001-1009. 

Stenger DA. and McKenna TM. Enabling Technologies for Cultured Neural Networks. New York Academic Press, 1994. 

Other Microtubule Cultured neural Mouse N/A Increased, Miura et al. 

Huszar, D Sharpe, A., and Jaenisch, R. (1991a). Migration and proliferation of cultured neural crest cells in W mutant neural crest chimeras. Development 112 131-141. 

Zhang et al.14 develop a neural network approach to bacterial classification using MALDI MS. The developed neural network is used to classify bacteria and to classify culturing time for each bacterium. To avoid the problem of overfitting a neural network to the large number of channels present in a raw MALDI spectrum, the authors first normalize and then reduce the dimensionality of the spectra by performing a wavelet transformation. 

For PyMS to be used for (1) routine identification of microorganisms and (2) in combination with ANNs for quantitative microbiological applications, new spectra must be comparable with those previously collected and held in a data base.127 Recent work within our laboratory has demonstrated that this problem may be overcome by the use of ANNs to correct for instrumental drift. By calibrating with standards common to both data sets, ANN models created using previously collected data gave accurate estimates of determi-nand concentrations, or bacterial identities, from newly acquired spectra.127 In this approach calibration samples were included in each of the two runs, and ANNs were set up in which the inputs were the 150 new calibration masses while the outputs were the 150 old calibration masses. These associative nets could then by used to transform data acquired on that one day to data acquired at an earlier data. For the first time PyMS was used to acquire spectra that were comparable with those previously collected and held in a database. In a further study this neural network transformation procedure was extended to allow comparison between spectra, previously collected on one machine, with spectra later collected on a different machine 129 thus calibration transfer by ANNs was affected. Wilkes and colleagues130 have also used this strategy to compensate for differences in culture conditions to construct robust microbial mass spectral databases. 

Altogether, there are many unknowns about carotenoid transport in the retina. However, present knowledge on carotenoid uptake in other cell types and the finding of multiple proteins potentially involved in carotenoid transport in the RPE and adjacent neural retina leads to the suggestion that several hypothetical pathways exist (Figure 15.3). Many such pathways can be easily tested in cultured RPE. 

Strategy for Adherent Cultures of Neural Stem Cells. 179... 

Nakaji-Hirabayashi T, Kato K, Arima Y, Iwata H (2007) Oriented immobilization of epidermal growth factor onto culture substrates for the selective expansion of neural stem cells. Biomaterials 28 3517-3529... 

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