Nausea calcium salts

Long-term use of calcium salts can cause the milk-alkali syndrome and alkalosis in conjunction with hypercalcemia and renal insufficiency (6). It presents acutely with headache, nausea, irritability, and weakness, or chronically with uremia, alkalosis, and hypercalcemia. Sustained high dosage and/or concurrent renal disease are common antecedents (7). 

Hypervitaminosis D apparently cannot arise from excessive exposure to sunlight but only occurs following inge.s-tion of large quantities of synthetic vitamin D for months The amount necessary has been estimated at 50,000 units or more in a person with normal parathyroid function. The mechanism may involve formation of excessive amounts of the vitamin D metabolite 25-OHD. Toxicity involves derangements of calcium metabolism, resulting in hypercalcemia and metastatic calcification of soft tissue. Most problems result from the hypercalcemia, which typically causes muscular weakness, anorexia, nausea, vomiting, and depression of the central nervous system (which can result in coma and death). In addition, deposition of calcium salts in the kidneys (nephrocalcinosis) and the tubules (nephrolithiasis)... 

Chelation therapy is usually the treatment of choice. Both CaNai-EDTA (calcium disodium salt of ethylenediaminetetraacetic acid) and British Antilewisite compound (BAL 2,3-dimercaptopropanol) are commonly used to remove lead from the body. Both are administered via intramuscular injection. BAL binds lead to sulfhydral groups and chelates metal from both inside and outside the cellular space. Lead removal through the bile and urine is increased within 30 min of administration. BAL is the common choice when there is known toxicity to the kidney, but it is contraindicated if there is liver failure or glucose-6-phosphate dehydrogenase deficiency. BAL treatment has produced a number of adverse reactions, including nausea, vomiting, tachycardia, and fever. 

Crystalline colourless solid. Found in many plants, particularly the leaves of the rhubarb plant and in the juice of wood sorrel. Salts of Sorrel, Salts of Lemon. Used as a bleach and ink stain remover. The concentrated solution is corrosive. Harmful if inhaled or absorbed through skin 15 g oral agonizing pain, nausea and vomiting with haematemesis. Lowers plasma calcium convulsions, tetany, tingling of mucous membranes. Renal damage tubular necrosis. Smallest lethal dose reported 3.8 g in a 16-year-old boy. 

GI Tract May cause abdominal pain and nausea. Although they are poorly absorbed through the intestines, inorganic manganese salts may produce hypoglycemia and decreased calcium blood levels if absorption occurs. 

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