National Academy of Clinical Biochemistry

Biochemistry, N.A.o.C (2000) Laboratory Guidelines for Screening, Diagnosis, and Monitoring of Hepatic Injury. National Academy of Clinical Biochemistry, Washington, DC, USA. 

Wu AH, Apple FS, Gibler WB, et al, National Academy of Clinical Biochemistry Standards of Laboratory Practice recommendations for the use of cardiac markers in coronary artery diseases. Clin Chem I 999 5 1 104-1 121. 

Linder MW, Keck PE Jr. Standards of laboratory practice antidepressant drug monitoring. National Academy of Clinical Biochemistry. Chn Chem 1998 44(5) 1073-84. 

The clinical laboratory has a vital role in both the diagnosis and management of diabetes mellitus. Some of the important parameters assayed are outlined in Table 25-4. In 2002 the National Academy of Clinical Biochemistry (referred to as the NACB) published evidence-based guidelines for laboratory analysis in diabetes mellitus. The guidelines were reviewed by the Professional Practice Committee of the ADA and were consistent in those areas where the ADA also published recommendations. Specific recommendations for laboratory testing based on pubfished data or derived from expert consensus are presented,A brief overview is presented here. 

Wu AHB, McKay C, Broussard LA, Hoffman RS, Kwong TC, Moyer TP, et al. National Academy of Clinical Biochemistry laboratory medicine practice guidelines recommendations for the use of laboratory tests to support poisoned patients who present to the Emergency Department. Chn Chem 2003 49 357-9. 

Numerous methods have been developed for assessing the concentrations of FT4 and FT3 in serum. These methods include direct assays that currently serve as reference methods and indirect assays that are more widely available for general laboratory use. The following section describes the principles of these methods and offers some guidelines for their use. The theoretical basis, analytical validity, and clinical utility of these methods have been discussed. Special reports from the Nomenclature Committee of the American Thyroid Association, the National Academy of Clinical Biochemistry, and the NCCLS also review some of the issues and concerns regarding free thyroid hormone measurements. 

Note The National Academy of Clinical Biochemistry practice guidehnes for the use of thyroid tests for the diagnosis and monitormg of thyroid disease was published in Thyroid 2003 13 1 126 and is also available on the NACB web site www.nacb.org. 

Baloch Z, Carayon P, Conte-Devobc B, Demers LM, Feldt-Rasmussen U, et al. Guidelines Committee, National Academy of Clinical Biochemistry. Laboratory medicine practice guidelines. Laboratory support for the diagnosis and monitoring of thyroid disease 2003 13 3-126. 

TSH levels are increased (overt hypothyroidism). Some authors reported that individuals with TSH values in the upper half of the reference range had a higher mean serum cholesterol level than those with low-normal TSH levels (Michalopoulou et al., 1998). Accordingly, some authorities (National Academy of Clinical Biochemistry) have proposed to lower the upper limit for TSH levels to 2.5mU/l (Baloch et ai, 2003 Wartofsky and Dickey, 2005). This criterion has been criticized because it would result in an overdiagnosis of subciinicai hypothyroidism and an increase in the number of patients on unnecessary replacement therapy (Surks et al., 2005 Dlez et al., 2005). 

Baloch, Z., Carayon, P, Conte-Devorx, B., Demers, L.M., Feldt-Rasmussen, U., Henry, J.E, Livosli, V.A., Niccoli-Sire, P., John, R., Ruj, J., Smyth, P.P., Spencer, C.A. and Stockigt, J.R. Guidelines Committee, National Academy of Clinical Biochemistry (2003). Thyroid 13, 3—126. 

Demers, L.M. and Spencer, C.A. (2002). In Laboratory Support for the Diagnosis and Monitoring of Thyroid Disease, (ed. National Academy of Clinical Biochemistry) Available at http //www.nacb.org/lmpg/thyroid lmpg pub.stm (accessed... 

Nichols JH, et al. Executive summary. The National Academy of Clinical Biochemistry Laboratory Medicine Practice Guideline evidence-based practice for point-of-care testing. Clin ChimActa 2007 379 14-28. 

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