Naphthyl methylcarbamate

Sideroff, S.I. and Santoluc, J.A. (1972). Behavioral and physiological effects of cholinesterase inhibitor carbaryl (1-naphthyl methylcarbamate). Physiology and Behavior 9, 459 62. 

Naphthylene)benzene, see Fluoranthene a-Naphthyl methylcarbamate, see Carbaryl 1-Naphthyl methylcarbamate, see Carbaryl... 

Vontor, T., Socha, J., and Vecera, M. Kinetics and mechanism of hydrolysis of 1-naphthyl, -methylcarbamate and N,N-dimethyl carbamates. Collect Czech. Chem. Common., 37 2183-2196, 1972. 

Comer et al. (2) therefore evaluated the effect of exposure to carbaryl (1-naphthyl methylcarbamate) on formulating plant workers and on workers applying carbaryl to fruit orchards with a tractor-drawn air-blast sprayer. However, information was still needed on the persistence of carbaryl in apple orchards and on the resultant exposure of workers who re-enter treated orchards. Further, no studies had been done on other types of crops. The present study was undertaken to determine the exposure of agricultural workers to carbaryl as a function of type of formulation, application equipment, application method, and type of work performed (i.e., mixer-loader, applicator, flagman, bystander, and apple thinners). 

The most widely used insecticides among the carbamates are Carbaryl (1-naphthyl methylcarbamate, Table 22) and Carbofuran (2,3-dihydro-2,2- dimethyl-7-benzofuranyl methylcarbamate. Table 21). 

Chemical Name carbamic acid, methyl-, 1-naphthyl ester 1-naphthalenol, methyl carbamate 1-naphthyl-V-methyl carbamate 1-naphthyl methylcarbamate 1-naphthalenyl methylcarbamate Uses contact insecticide used to control most insects on fruits, vegetables, and ornamentals also used as growth regulator for fruit thinning of apples. 

NAPHTHYL METHYLCARBAMATE see CBM750 1-NAPHTHYL N-METHYLCARBAMATE see CBM750 a-NAPHTHYL METHYLCARBAXIATE see CBM750 a-NAPHTHYL N-METHYLCARBAMATE see CBM750 1-NAPHTHYL-N-METHYL-KARBA.MAT see CBM750... 

Carbary I (1-naphthyl methylcarbamate) is a chemical in the carbamate family used chiefly as an insecticide. It is a colorless white crystalline solid. Carbaryl disrupts the nervous system by adding a carbamyl moiety to the active site of the acetylcholinesterase enzyme, which prevents it from interacting with acetylcholine.1 It is classified as a likely human carcinogen by the EPA. The pesticide is used indiscriminately, so the toxicity has raised public concern about the ecosystem and human health. Carbaryl is lethal to many non-target insects such as the honeybee. Accumulation of the pesticide occurs in many aquatic organisms such as catfish and algae.2 Due to public health and ecosystem concerns a number of analytical procedures have been used to determine carbaryl concentrations. 

The differences observed between chlorthiophos, carbosulfan, and other pesticides that have been examined appear to be largely due to their rate of absorption, and anti-ChE activity. These relationships were recently examined for carbaryl [1-naphthyl methylcarbamate], parathion ( 9) and thiodicarb [dimethyl N,N (thiobis[(methylimido)carbonyloxy]] bis [ethanimidothioate]] (10) in the Sprague-Dawley rat and are reviewed in this paper. 

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