Naphthalene, 1-methyl-1,2,3,4-tetrahydro

Limonene, sylvestrene and terpinene are all reduced to l-methyl-4-isopropyl-cyclohexane by this method, naphthalene gives tetrahydro-naphthalene, and acenaphthene behaves similarly. 

Methyl-1,2,3,4-tetrahydro naphthalene Decahydro-2-methylnaphthalene Decahy dro-1 -ethyl-5 -methy lnaphthalene 1 -Methy lperhy drophenanthrene... 

TETRAHYDRO-2-1ODO-, METHYL ESTER, 51, 112 Naphthalene-1-carbonitrile, 50, 20... 

Naphthalene carbamic acid, l,2,3,4-tetrahydro-2-iodo-, methyl... 

Naphthalene-l-ol, 1-2 3-4-tetrahydro, cis-2-iso-propenyl-8-methyl Lf Naphthoquinone, 1-4, 2-3-6-trimethyl Lf Nectarin I ... 

Methoxy-7-methoxycarbonyl-1,2,3,4-tetrahydronaphthalene 2-Naphthalene-carboxylic acid, 5,6,7,8-tetrahydro-3-methoxy-, methyl ester (78112-34-2), 65, 98 Methyl acrylate (96-33-3), 66, 54, 59 dimerization by Pd(II), 66, 52 Methylamine, N-benzylidene-, 65, 140 METHYL 4-0-BENZOYL-6-BROMO-6-DEOXY-a-0-GLUCOPYRANOSIDE ... 

On gradual heating to 300 C with four equivalents of antimony(V) fluoride and simultaneous distillation of the reaction product, octafluoronaphthalene is transformed to perfluoro-1,2.3,4-tetrahydronaphthalene in 77% yield.94 Under similar conditions 2-substituted hepta-fluoronaphthalenes(R = H, Cl) give a mixture of octafluoronaphthalene and the corresponding 6-substituted undecafluoro-1,2,3,4-tetrahydronaphthalenes in about 40 % yield while the major fluorination product of the compound with R = CF3 is perfluoro(6-methyl-1,2,3,4-tetrahydro-naphthalene) (50%).97... 

Methoxy-7-methoxycarbony1-1,2, 3,4-tet rahydronaphthalene 2-Naphthalene-carboxylic acid, 5,6,7,8-tetrahydro-3-methoxy-, methyl ester (10) ... 

Pravastatin was isolated as products of enzymatic hydroxylation by some kinds of microorganisms of [lS-[l-a(R ),7p,8P(2S, 4S )8a 3]]-2-methylbutanoic acid l,2,3,7,8,8a-hexahydro-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2))-pyran-2-yl)ethyl]-l-naphthalenic lactone (campactin) or their carboxylic acid or their salts (products of animal metabolism of microorganisms from the genera Nocardia, Streptomyces et cetera). 

Methylene-1-oxo-1,2,3,4-tetrahydro-naphthalene l(2//)-Naph-thalenone, 3,4-dihydro-2-methylene- (8,9) (13203-73-1) N-Methylanilinium trifluoroacetate Aniline, A-methyl-, trifluo-roacetate (8) Benzenamine, /V-methyl-, trifluoroacetate (9) (29885-95-8)... 

Pentane-washed NaH (4.1 g) was suspended in 70 ml DMSO and a solution of ethyl (E,E)-6-(diethoxyphosphinyl)-3-methyl-2,4-hexdienolate (24.5 g) dissolved in 70 ml DMSO added. The reaction was stirred for 30 minutes at ambient temperature and 2-formyl-3-hexyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalene (11.3 g) dissolved in 70 ml DMSO and 35 ml THE added. The mixture was stirred 2 hours and the product precipitated in ice water acidified with 6M HCl. The mixture was extracted with EtOAc and purified by flash chromatography on silica gel with hexane/methyl t-butyl ether, 98 2, and the product isolated as a pale yellow oil. 

Naphthalene (49) reacts with sodium in liquid ammonia to form a red complex which is quenched by methanol to form the 1,4-dihydro derivative (51), and may therefore be assumed to be the dianion (50).- If alcohol is present in the reaction mixture, then the 1,4,5,8-tetrahydro derivative (52) is formed (Scheme 6). 1-Naphthyl derivatives are reduced in the unsubstituted ring, whereas there is a maiked preference for reduction of the substituted ring in 2-methyl- and 2-methoxy-substituted isomers. This preference is not as well defined for bulkier substituents, however, and is reversed in the case of 2-f-butylnaphthalene further details are in a 1970 review. Because of the facile isomerization of the 1,4-dihydro isomers to conjugated derivatives, overreduction occurs readily and ether groups are fairly readily hydrogenolyzed. It is therefore important to select the reaction conditions with care.- ... 

We have examined experimentally the response of the light-scattering instrument to scattering using the same polystyrene standards in solvents of different index of refraction. We made a series of measurements on two polystyrene standards (Millipore nominal = 8500, P/N 25171, Lot 80314 and Waters nominal = 110,000, P/N 41995, Lot 70111) dissolved in five solvents [acetone, methyl ethyl ketone (MEK), tetrahydro-naphthalene, THE, and toluene]. 

Figure 6.2.7. Tentatively assigned spectrum for methyl 2-methyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylate MW = 204 (ret. time 79.0 min.).

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