Names for drugs

Assist in Standardization of Nomenclature. The profusion of trade names, initials, numbers, and combinations thereof for pesticides contributes to misuse and errors in the handling of these preparations. The coining of common or generic names for pesticides is a recent and commendable innovation in this field of science. It presents many problems which require the services of many groups. The many years of experience of the Council on Pharmacy and Chemistry in the development of generic names for drugs is at the disposal of the committee in its consideration of nomenclature problems. 

Official names, Street names This section lists the alternate names for a substance, including brand names, generic names, and chemical names for drugs, as well as common street names for drugs and other substances. 

The ethical case for a more personal medicine markets, namely for drugs affecting only a fraction of the genome pool, was already promoted in 1994. Writing in 1997, Classen found that between 1.6 billion and 4.2 billion were being spent each year in the United States for additional treatments to deal with adverse reactions (Classen, 1997), and later Lazarou estimated adverse reactions to have caused over 100,000 deaths during 1994 (Lazarou, 1998). Genetic tests would enable the physician to avoid some of these risks and so treat patients more effectively. 

Let us look now at the dispute concerning tradenames and generic names for drugs. The average physician has viewed this tug-of-war with... 

Coronary vasodiiator Older incorrect name for drugs useful in angina. Drugs that relieve angina of effort do not act primarily through coronary vasodilation some potent coronary vasodilators are ineffective in angina... 

The Naming of Chiral Drugs. The nomenclature of chiral compounds is difficult and sometimes confusing. We have already introduced the prefixes R and S, (- -) and (—), and D and L. We have already seen many common names for drugs that have an implied chirality, as in methamphet-amine and ephedrine. The hyphenated prefixes R/S, D/L, and + / — render the alphabetic indexing of pharmaceutics problematic. One approach to this problem that has been used to help with this issue is to select drug names where the chirality has been imbedded into the common chemical name. One example that we have discussed is esomeprazole,... 

Description of Method. Fluoxetine, whose structure is shown in Figure 12.31a, is another name for the antidepressant drug Prozac. The determination of fluoxetine and its metabolite norfluoxetine. Figure 12.31 b, in serum is an important part of monitoring its therapeutic use. The analysis is complicated by the complex matrix of serum samples. A solid-phase extraction followed by an HPLC analysis using a fluorescence detector provides the necessary selectivity and detection limits. 

International Nonproprietay Names for Pharmaceutical Substances, Cumulative Eist No. < , Wodd Health Organization, Geneva, Switzedand, 1988 WHO Drug Inform. 6(3) and Special Section (1992). 

Explains the reason for drug therapy, including the type of antidepressant prescribed, drug name, dosage, and frequency of administration. 

X 16.101 cis-Platin is an anticancer drug with a structure jQ that can be viewed on the Web site, (a) What is the formula and systematic name for the compound cis-jf Platin (b) Draw any isomers that are possible for this compound. Label any isomers that are optically active, (c) What is the coordination geometry of the platinum atom ... 

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