Mycoplasma capricolum

Klebsiella pneumoniae [22] <13> Mycoplasma capricolum [26] <14> Streptomyces lividans [28] <15> Streptomyces coelicolor [28] <16> Streptomyces griseofuscus [28]... 

Andersen, H., Christiansen, G., and Christiansen, C. 1984, Electrophoretic analysis of proteins from Mycoplasma capricolum and related serotypes using extracts from intact cells and from minicells containing cloned mycoplasma DNA. J Gen Microbiol 130 1409-1418. 

Because of its occurence in diseased tissue, the mode of association of cholesterol esters with biomembranes is of interest. Possible modes of association could be droplets within the hydrophobic core of the membrane bilayer, binding to membrane protein or as part of membrane attached serum lipoproteins. A potentially useful model system for investigating this association is the membrane of the microorganism Mycoplasma capricolum. The Mycoplasma due to their simplicity have served as model membrane systems in many studies. As mentioned previously, cholesterol esters show complex behavior that is a function of thermal history, impurities and physical packing constraints. Using DSC on native membranes and extracted membrane material, it was possible to demonstrate that the majority of cholesterol esters associated with the membranes of M. capricolum exist as relatively large and pure liquid droplets (17). 

Francisella tularensis Mycoplasma capricolum subspecies capripneumoniae... 

Ohkubo S, Muto A, Kawauchl Y. Yamao F, Osawa S. The ribosomal protein gene cluster of Mycoplasma capricolum. Mol Gen Genet 1987 210 314-322. 

Dahl J S, Dahl C E, Bloch K 1980 Sterols in membranes Growth characteristics and membrane properties of Mycoplasma capricolum cultured on cholesterol and lanosterol. Biochemistry 19 1467-1472... 

All these results taken together indicate that cyclopropylsterols can replace effectively A -sterols as membrane components in higher plants as well as in other organisms such as the GL7 yeast mutant (7), Mycoplasma capricolum (8) or Tetrahymena pyriformis (9). Further investigations are necessary to determine whether other sterol structures like A -sterols or A ,14a-methylsterols are also suitable for playing a similar role. 

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