Multiple stage mass spectrometry

MS11 Multiple-stage mass spectrometry tandem mass spectrometry... 

Waridel P, Wolfender J-L, Ndjoko K, Hobby KR, Major HJ and Hostettmann K. 2001. Evaluation of quadrupole time-of-flight tandem mass spectrometry and ion-trap multiple-stage mass spectrometry for the differentiation of C-glycosidic flavonoid isomers. J Chromatogr A 926(1) 29-41. 

Multiple-Stage Mass Spectrometry (MS") Multiple stages of precursor ion m/z selection followed by product ion detection for successive progeny ions. 

The most recent modification of the NBD-Cl method involves a further improvement in its qualitative support (616). It involves the infusion of the extract employed for thin-layer chromatography via an electrospray interface into a mass spectrometer operating in the multiple-stage mass spectrometry mode, thus allowing confirmation of suspect results. The cleanup of the thyroid gland samples was also performed with a selective extraction procedure, based on the specific complex formation of the thiouracil, methylthiouracil, propylthiouracil and phenylthiouracil, tapazole, and mercaptobenzimidazole residues with mercury ions bound in a Dowex 1-X2 affinity column. 

MSn Abbreviation for multiple stage mass spectrometry/mass... 

Waridel, P Wolfender, J.-L. Ndjoko, K. Hobby, K.R. Major, H.J. Hostettmann, K. Evaluation of Quadrupole Time-of-Flight Tandem Mass Spectrometry and Ion-Trap Multiple-Stage Mass Spectrometry for the Differentiation of C-glycosidic Flavonoid Isomers, J. Chromatogr. A 926(1), 29 1 (2001). 

Kamel, A. M., Fouda, H. G., Brown, P. R., and Munson, B. (2002). Mass spectral characterization of tetracyclines by electrospray ionization, H/D exchange, and multiple stage mass spectrometry. J. Am. Soc. Mass Spectrom. 13, 543-557. 

Wey, A. B. and Thormann, W. Capillary electrophoresis and capillary electrophoresis-ion trap multiple-stage mass spectrometry for the differentiation and identification of oxycodone and its major metabohtes in hytmasttssiae. J Chrorruttogr B Analyt Technol Biomed Life Sci, 770,191, 2002. 

Crescenzi, C. Bayoudh, S. Cormack, P.A.G. Klein, T. Ensing, K. Determination of clenbuterol in bovine liver by combining matrix solid-phase dispersion and molecularly imprinted solid-phase extraction followed by liquid chromatography/electrospray ion trap multiple-stage mass spectrometry. Anal. Chem. 2001, 73, 2171 2177. 

Liu J, Yang X, He J, Xia M, Xu L, Yang S (2007) Structure antilysis of triterpene saponins in Polygala tenuifolia by electrospray ionization ion trap multiple-stage mass spectrometry. J Mass Spectrom 42 861-873... 

Mohamed R, Gremaud E, Richoz-Payot J, Tabet JC, Guy PA (2006) Mass spectral characterization of ergot alkaloids by electrospray ionization, hydrogen/deuterium exchange, and multiple stage mass spectrometry usefulness of precursor ion scan experiments. Rapid Commun Mass Spectrom 20 2787-2799... 

Kamel A, Munson B. Collision induced dissoeiation studies of alkali metal adducts of tetracyclines and antiviral agents by electrospray ionization, hydrogen/deuterium exchange and multiple stage mass spectrometry. Eur J Mass Spectrom. 2008 14 281-97. 

Roush R A, Cooks R G 1984 Characterization of alkaloids and other secondary metabolites by multiple stage mass spectrometry. J Nat Prod 47 197-214... 

In principle, both instrumental concepts can be expanded to allow for multiple-stage mass spectrometry, i.e., multiple stages of precursor ion selection followed by product ion detection for successive n generation product ions [6]. While it is convenient to talk about MS/MS, acronyms like MS/MS/MS are clearly out of place. Therefore, it is common practice to use MS, MS, and generally MS" to denote the number of stages of a tandem mass spectrometric experiment. Accordingly, in the sequential fragmentation scheme... 

Glish, G.L. Multiple Stage Mass Spectrometry the Next Generation Tandem Mass Spectrometry Experiment. Analyst 1994,119, 533-537. 

This symbol refers to multistage MS/MS experiments designed to record product ion spectra where n is the number of product ion stages (fragment ions). For ion traps, sequential MS/MS experiments can be undertaken where n>2 whereas for a simple triple quadrupole system n = 2, -> Multiple-stage mass spectrometry. 

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