Multifunctional polymer

In a recent study, some authors proposed the employment of thiolated polymers obtained by the immobilization of thiol groups on well-established multifunctional polymers such as poly(acrylates) and chitosans as functional agents having mucoadhesive, penetration enhancement, and enzyme-inhibiting properties [94,95]. 

In the near future, the use of multifunctional polymer-based materials with separation/selective transport capabilities is also to be expected in the design of production systems with integrated environmental protection or inthe combination of chemical reactions and separation by attaching a catalytic functionality to the respective material [1]. Thus, those multifunctional materials should contribute materially to the development of clean energy and/or energy saving and therefore sustainable production technologies. In connection with these perspectives, there is considerable interest in new/modified polymer-based materials with tailored transport/catalytic properties. Also, many sensor applications are based on controlled permeation. 

Multifunctional carrier matrices offer various advantages for oral drug delivery. Their application for oral drug delivery is described in Chapter 8. Generally, such carriers can be used either to protect the drug from enzymatic degradation via steric hindrance or to directly inhibit enzymes. Multifunctional polymers that can inhibit GI proteolytic enzymes per se are polyacrylates and modifications thereof as well as polymer-inhibitor... 

Table 8.1 Examples of multifunctional polymers and their properties...

Shen, K.K. Kochesfahani, S. Jouffret, F. Zinc borates as multifunctional polymer additives. Polym. Adv. Technol. 2008, 19, 469474. 

A substrate functionalized with proper molecules can be used to anchor particles on its surface via surface exchange reaction, leading to controlled assembly of the particles. This self-assembly technique is known as molecule-mediated self-assembly and is commonly used for constructing various composite nanostructures [49-55]. Due to their excellent adhesion capability to various substrates, multifunctional polymers are routinely applied as templates to mediate the assembly of the particles. The assembly is carried out as follows a substrate is immersed into a polymer solution, and then rinsed, leading to a functionalized substrate. Subsequently, this substrate is dipped into the nanoparticle dispersion and then rinsed, leaving one layer of nanoparticles on the substrate surface. By repeating this simple two-step process in a cyclic fashion, a layer-by-layer assembled poly-mer/nanoparticle multilayer can be obtained. 

Ranucci, F.. and Bignotti, F., New basic multifunctional polymers. VIII. Poly(amino-thioether-ketone)s, Chim. Ind., 72,799, 1990,... 

Ranucci, K. and Femui, P., New basic multifunctional polymers. VII. A polyfaniino-thiocther-phenol) by polycondcasalion of 2,2 -( 1.4-piperazincdiyl)diclhanclhiol with 2,6-bis(dimethylamin(Mnelhyl)-4-mcth-ylphenol, Chan. Ind.. 72, 795, 1990. 

The dynamic tracer pulse technique used in this work facilitates the study of BV and how BV might be altered because of high levels of organic compounds or humidity. Based on competitions of the various, selected probes, cursory information about surface sites can be obtained for a prospective adsorbent such information is especially useful for multifunctional polymers. This technique can also permit the fine tuning of the environmental collection strategy through the examination of retentions on mixed adsorbents or multiple adsorbent beds. The use of dynamic TPC with the polyimides demonstrated that these materials are more sensitive, in terms of BV of the tested probe molecules, to the effects of humidity than is Tenax-GC. 

Polydiaminophenazine, polyquinoxaline, polydiaminopyridine, polyphenothiazine as novel multifunctional polymers from aromatic diamines by oxidative polymerizations 02CRV2925. 

Photorefractivity in an organic material was first reported in 1990 [36] by the ETH Zurich group in an organic single crystal. The same year a group at Eastman Kodak developed a multifunctional polymer that showed photoconductivity and... 

Electropolymerization of polymers directly onto the surface of an electrode has been used for a number of enzyme-based biosensors. By polymerizing from a solution containing the monomer, as well as the other components of the sensor, enzymes for example, a multifunctional polymer film can be fabricated. As the polymer film grows on the electrode, the enzyme and other components are entrapped in the film [9]. GOD and other enzymes have been incorporated into sensors using electropolymerization. Advantages of electropolymerization are that the film thickness can be easily controlled by the amount of polymerization charge passed, and that the polymer film is deposited only on the sensing electrode. 

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