Multicollector inductively coupled plasma

Nakai S, Fidcuda S, Nakada S (2001) Thorium isotopic measurements on silicate rock samples with a multicollector inductively coupled plasma mass spectrometer. Analyst 126 1707-1710... 

Jackson SE, Gunther D (2003) The nature and sources of laser induced isotopic fractionation in laser ablation-multicollector-inductively coupled plasma-mass spectrometry. J Anal At Spectrom 18 205-212 Jiang S-J, Houk RS, Stevens MA (1988) Alleviation of overlap interferences for determination of potassium isotope ratios by Inductively-Coupled Plasma Mass Spectrometry. Anal Chem 60 1217-1220 Lam JWH, Horlick G (1990) A comparison of argon and mixed gas plasmas for inductively coupled plasma-mass spectrometry. Spectrochim Acta Part B 45 1313-1325 Langmuir I, Kingdon KH(1925) Thermionic effects caused by vapours of alkali metals. Phil Trans R Soc A107 61-79... 

Russel WA, Papanastassiou DA, Tomhrello TA (1978) Ca isotope fractionation on the Earth and other solar system materials. Geochim Cosmochim Acta 42 1075-1090 Sakata KI, Kawahata K (1994) Reduction of fundamental polyatomic ions in inductively coupled plasma mass spectrometry. Spectrochim Acta Atom Spectrosc PartB 49 1027-1038 Siehert, C, Nagler, TF, Kramers JD (2001) Determination of molybdenum isotope fractionation by doublespike multicollector inductively coupled plasma mass spectrometry. Geochem Geophys Geosyst 2 2000GC000124... 

Samples were prepared for Cu isotope analysis on the Multicollector Inductively-Coupled Plasma Mass Spectrometer (MC-ICPMS) at University of Arizona. The Cu-rich samples were loaded and dissolved in pure HNO3 and the Cu-poor samples were loaded and dissolved in a mixture of HCI and HNO3, Chromatographic separation of the Fe and Cu ions was deemed necessary for the Cu-rich samples. The diluted solutions were injected into the MC-ICPMS using a microconcentric nebulizer. Samples were run numerous times to increase precision. The Cu isotope ratios are reported in conventional per mil notation, relative to the NIST 976 standard. Mass bias was also accounted for by bracketing methods with the NIST 976 standard. 

The samples purified with lEC were diluted to approximately 100 ppb Cu. These samples were injected into a Multicollector Inductively-Coupled-Plasma mass spectrometer (MC-ICPMS, Micromass Isoprobe at the University of Arizona and Neptune at Washington State University) in low resolution mode using a microconcentric nebulizer to increase sensitivity for the samples with lower concentrations of copper. The nebulizer flow was adjusted so that the intensity of the Cu beam remained constant at 2 volts. Both on and off peak blank corrections were applied to the data and yielded the same result. 

The uranium series dating is based on the determination of the U/ °Th or 235 /23 Isotopic ratio measurements can be made by means of a mass spectrometer. Multicollector inductively coupled plasma mass spectrometry (MC-ICP-MS)... 

Isotope ratios provide insight into the physical and chemical processes that cause alteration of their values. Their application is expanding as analytical procedures become more sophisticated and sensitive, and as the extent of scientific knowledge increases. As in many fields, much work done today would have been impossible a few years ago. With the advent of multicollector inductively coupled plasma (ICP) mass spectrometers, it is probable that routine use of thermal ionization will diminish, but it seems that it will always play a role in applications in which utmost sensitivity is required. 

Pearson N. J., Alard O., Griffin W. L., Jackson S. E., and O Reilly S. (2002) In situ measurement of Re-Os isotopes in mantle sulfides by laser ablation multicollector inductively coupled plasma mass spectrometry anaytical methods and preliminary results. Geochim. Cosmochim. Acta 66, 1037-1050. 

The advances in instrumentation and particularly the arrival of the multicollector inductively coupled plasma mass spectrometers (MC-ICPMS) opened a window for a number of new tracers that were difficult to tackle with the old instrumentation. A pattern for seawater evolution is thus emerging for isotopes of boron and calcium. 

LA-MC-ICP-MS Laser ablation multicollector inductively coupled plasma mass spectrometry... 

Bommer et al. [46] report on the differentiation of batches of diazepam using IRMS. The differences in isotopic composition were primarily due to differences in the isotopic composition of the starting materials. Santamaria-Fernandez et al. [47] discussed the combination of isotope values measured using multicollector inductively coupled plasma mass spectrometry (MC-ICP-MS) and IRMS to assist in the detection of counterfeit pharmaceutical tablets (Heptodin ). 

Santamaria-Fernandez, R., Hearn, R., Wolff, J-C. (2009) Detection of counterfeit antiviral drug Heptodin and classification of counterfeits using isotope amount ratio measurements by multicollector inductively coupled plasma mass spectrometry (MC-ICEMS) and isotope ratio mass spectrometry (IRMS). Sci. Justice, 49(2), 102-106. 

Copeland, S.R., Sponheimer, M., Le Roux, P.X, Grimes, V, Lee-Thorp, X A., De Ruiter, D.X, Richards, M.P. (2008) Strontium isotope ratios (87Sr/86Sr) of tooth enamel a comparison of solution and laser ablation multicollector inductively coupled plasma mass spectrometry methods. Rapid Communications in Mass Spectrometry, 22(20), 3187-3194. 

High -precision measurement of mercury isotope ratios in sediments using cold vapor generation multicollector inductively coupled plasma mass spectrometry. Anal. Bioanal. Chem., 384, 1470-1478. 

Schoenber, R., Nagler, T.F., and Kramers, J.D. (2000) Precise Os isotope ratio and Re-Os isotope dilution measurements down to the picogram level using multicollector inductively coupled plasma mass spectrometry. Int. J. Mass Spectrom., 197, 85-94. 

The corabination of an inductively coupled plasma ion source and a magnetic sector-based mass spectrometer equipped with a multi-collector (MC) array [multicollector inductively coupled plasma mass spectrometry (MC-ICP-MS)] offers precise and reliable isotope ratio data for many solid elements. In fact, MC-ICP-MS provides data, the trueness (accuracy) and precision of which is similar to, or, in some cases, even superior to, that achieved by thermal ionization mass spectrometry (TIMS), considered the benchmark technique for isotope ratio measurements of most solid elements [1], The basic strength of ICP-MS lies in the ion source, which achieves extremely high ionization efficiency for almost all elements [2, 3]. Consequently, MC-ICP-MS is likely to become the method of choice for many geochemists, because it is a versatile, user-friendly, and efficient method for the isotopic analysis of trace elements [4-8], The ICP ion source also accepts dry sample aerosols generated by laser ablation [9-16], The combination of laser ablation (LA) with ICP-MS is now widely accepted as a sensitive analytical tool for the elemental and isotopic analysis of solid samples. 

Hintelmann, H. and Lu, S.Y. (2003) High precision isotope ratio measurements of mercury isotopes in cinnabar ores using multicollector inductively coupled plasma mass spectrometry. Analyst, 128, 635-638. 

Gehrels, G.E., Valencia, V.A., and Ruiz, J. (2008) Enhanced precision, accuracy, efficiency, and spatial resolution of U-Pb ages by laser ablation-multicollector-inductively coupled plasma-mass spectrometry. Geochem. Geophys. Geosyst., 9, Q03017. 

J.C. (2010) Application of laser ablation multicollector inductively coupled plasma mass spectrometry for tbe measurement of caldum and lead isotope ratios in packaging for discriminatory purposes. Rapid Commun. Mass Spectrom., 24, 1993—1999. 

Murphy, M.F., JatufF, F., and Chawla, R. (2008) Comparison of optimised germanium gamma spectrometry and multicollector inductively coupled plasma mass spectrometry for the determination of Cs, Cs and Fu single ratios in highly burnt UO2. Nud. Instrum. Methods Phys. Res. A, 589 (3), 425-435. 

Jackson, S. E. and Gtlnther, D. (2003) The nature and sources of laser induced isotopic fractionation in laser ablation-multicollector-inductively coupled plasma-mass spectrometry. J. Anal. At. Spectrom., 18, 205-12. 

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