Monotard - Insulin

Insulin Zinc Suspension. Lente Insulin Lente lie-tin Insulin Novo Lente Human Monotard Insulin Ultra -card Lentard Monotard Semitard Ultratard. Sterile suspension, in a buffered water medium, of insulin modified by the addition of zinc chloride in a manner such that the solid phase of the suspension consists of a mixture of crystals and amorphous materia] in a ratio of approx 7 3 Hallas -Moller, Lancet 267, 1029 (1954). Contains 40 Or 80 U.S.P, insulin units/ml. Prepn of amorphous zinc insulin suspension Petersen et aL, U.S. pat, 2 82,203 (1959 to Novo Terapeu-tisk Lab. A IS). 

Actrapid/Velosulin/ Monotard/ Insulatard/ Protaphane/ Mixtard/ Actraphane/ All contain recombinant human insulin produced in S. cerevisiae formulated as short/ intermediate/long acting product) Identical to native human insulin Novo Nordisk 2002 (EU)... 

Human insulin from E coli is available for clinical use as Humulin (Lilly) and dispensed as either regular, NPH, lente, or ultralente Humulin. Human insulin prepared biosynthetically in yeast is marketed by Novo Nordisk as human insulin injection in regular, lente, and NPH forms Novolin R, Monotard Human Insulin (Novolin L), and Novolin N. The same company also produces a human insulin marketed as Velosulin (regular) that contains a phosphate buffer. This reduces aggregation of regular insulin molecules when used in infusion pumps. However, because of the tendency of phosphate to precipitate zinc ions, Velosulin should not be mixed with any of the lente insulins. 

USA hu insulin Zn suspension 30/70 insulin Novolin L Monotard, Human Monotard Recombinant human insulin, zinc suspension, mixture of physical forms following expression in Saccharomyces cerevisiae Diabetes... 

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