Molecular wire effect

Scheme 2 Illustration of molecular wire effect using fluorescence quenching of CPs as an example...

Yaliraki SN, Ratner MA (1998) Molecule-interface coupling effects on electronic transport in molecular wires. J Chem Phys 109(12) 5036-5043... 

Kushmerick JG, Holt DB, Pollack SK, Ratner MA, Yang JC, Schull TL, Naciri J, Moore MH, Shashidhar R (2002) Effect of bond-length alternation in molecular wires. J Am Chem Soc 124 10654-10655... 

As a class of n-type organic semiconductors, PBI derivatives have received considerable attention for a variety of applications [312, 313], for example, for organic or polymer light-emitting diodes (OLEDs and PLEDs) [314, 315], thin-film organic field-effect transistors (OFETs) [316, 317], solar cells [318, 319], and liquid crystals [320]. They are also interesting candidates for single-molecule device applications, such as sensors [321], molecular wires [322], or transistors [141]. 

R. E. Martin, T. Mader, F. Diederich, Monodisperse Poly(triacetylene) Rods Synthesis of a 11.9 nm Long Molecular Wire and Direct Determination of the Effective Conjugation Length by UV/Vis and Raman Spectroscopies , Angew. Chem Int. Ed. Engl. 1999,38, 817-821. 

As a consequence, any nonspecific adsorption of protein to the interface will also cause an attenuation in electrochemistry. Hence, the antifouling layer is required to ensure the attenuation of the electrochemistry associated with the presence of antibodies is due to a specific interaction with the binding epitope on the molecular wire rather than any nonspecific effects. The ability of this layer to resist nonspecific adsorption of proteins, as well as preventing electroactive species reaching the electrode, was demonstrated by Liu and Gooding [131] previously and is demonstrated in the current paper via controls that show there is little attenuation in the ferrocene electrochemistry if a different antibody is used or if the biotin epitope is absent from the interface. 

In reporting the bandstructure calculations for DNA-based molecular wires, we first focus on the kind of information that may be extracted from the study of model nucleobase assemblies, and then analyze the attempts to treat realistic molecules. Finally, we give a brief account of the environmental effects, e.g., the presence of water molecules and counterions. 

Thus, the caroviologen approach does produce functional molecular wires that effect electron conduction in a supramolecular-scale system. Incorporation into black lipid bilayer membranes (BLM) should allow further investigations of the electron-transfer properties of these caroviologens and positive preliminary results have been obtained [8.145a]. A theoretical investigation of electron conduction in molecular wires has been made [8.145b]. 

Debieu D, Deschavanne PJ, Midander J, Larsson A, Malaise EP (1985) Survival curves of glutathione synthetase deficient human fibroblasts correlation between radiosensitivity in hypoxia and glutathione synthetase activity. Int J Radiat Biol 48 525-543 Debije MG, Milano MT, Bernhard WA (1999) DNA responds to ionizing radiation as an insulator not as a molecular wire". Angew Chem Int Ed Engl 38 2752-2756 Debije MG, Razskazovskiy Y, Bernhard AW (2001) The yield of strand breaks resulting from direct-type effects in crystalline DNA X-irradiated at 4 K and room temperature. J Am Chem Soc 123 2917-2918... 

Priyadarshy S, Risser SM, Beratan DN (1996) DNA is not a molecular wire Protein-like electron-transfer predicted for extended Ti-electron system. J Phys Chem 100 17678-17682 Purdie JW (1980) Dephosphorylation of WR-2721 to WR-1065 in vitro and effect of WR-1065 and misonidazole in combination in irradiated cells. In Brady LW (ed) Radiation Sensitizers, pp 330-333... 

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